Janugliptin Duo Tablets 50/1000 mg

Adult dose

This medication is typically taken twice a day with food, and the dosage is gradually increased to reduce gastrointestinal side effects associated with metformin. 1. For patients who are not currently treated with metformin: - Initial dose: Take this medication 50/500 mg, 1 tablet twice a day - When increasing the dose: Take this medication 50/1000 mg, 1 tablet twice a day 2. For patients currently undergoing treatment with metformin:

This medication contains two components, sitagliptin and metformin, which help control blood sugar levels. Firstly, sitagliptin may cause allergic reactions in some patients, and in severe cases can lead to anaphylaxis or skin conditions. Additionally, there have been reports of serious side effects including pancreatitis, an inflammation of the pancreas, so if symptoms such as abdominal pain or vomiting occur during use, immediate consultation with a physician is necessary. Metformin can rarely cause lactic acidosis, a serious metabolic disorder, which may present with symptoms like muscle pain, difficulty breathing, and abdominal pain, so caution is required. This medication should not be used in patients with moderate to severe renal impairment, acute heart problems or heart failure, pregnant or breastfeeding women, and patients with certain acute illnesses. It is essential to maintain regular meals and exercise while taking this medication, and to closely observe for any sudden weight changes or fluctuations in blood sugar control. Additionally, co-administration with other hypoglycemic agents or alcohol may increase the risk of hypoglycemia, so consultations with the prescribing doctor are necessary before taking any additional medications. It is important to regularly check kidney function and conduct blood tests to monitor for potential side effects of the medication. Before and after surgery, it may be necessary to temporarily discontinue use of this medication, so it is important to speak with healthcare professionals. Finally, this medication has not been established for safety and efficacy in children, and dose adjustments may be necessary for elderly patients considering kidney function.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, rash, skin vasculitis, Stevens-Johnson syndrome and other exfoliative skin diseases, acute pancreatitis, acute renal failure, difficulty breathing, severe joint pain with disability, blistering similar to pemphigus, unstable angina, metabolic acidosis, severe hypoglycemia, difficulty breathing

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory tract infections
• nasopharyngitis
• headache
• hypoglycemia
• constipation
• muscle pain

This medication should be stored in a sealed container to prevent the ingress of air and moisture, and it is safest to keep it at room temperature between 1 to 30 degrees Celsius. Therefore, avoid places that are too hot or too cold, and it is vital to store it at appropriate temperatures to maintain its effectiveness.

Appearance

Reddish-brown oval film-coated tablet

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle