Janustine Met Tablet 50/500 mg

Adult dose

This medication is generally taken twice daily with food. The initial dose is determined based on the patient's current therapy and the dosage is gradually increased to minimize gastrointestinal adverse effects from metformin. 1. Patients not previously treated with metformin: - The initial dose is this medication 50/500 mg taken twice daily, 1 tablet per dose. - For titration, this medication 50/1000 mg taken twice daily, 1 tablet per dose.

This medication contains two components, sitagliptin and metformin. First, an allergic reaction may occur when taking this medication, so if symptoms such as skin rash, itching, or difficulty breathing arise, it should be discontinued immediately and a doctor consulted. Second, inflammation of the pancreas, known as pancreatitis, may occur, so sudden abdominal pain, vomiting, or nausea should be reported to medical personnel immediately. Third, the metformin component can rarely cause a serious condition called lactic acidosis, which is characterized by excessive accumulation of lactic acid in the body and can lead to dangerous conditions, with symptoms like weakness, muscle pain, difficulty breathing, and abdominal pain. If these symptoms occur, this medication should be stopped immediately, and the patient should go to a hospital. Fourth, patients with impaired kidney function or liver dysfunction should avoid using this medication and undergo regular kidney function tests. Fifth, excessive alcohol consumption can increase the risk of side effects from this medication, so it is safest to avoid drinking alcohol. Sixth, this medication can cause hypoglycemia, so caution should be exercised when skipping meals or engaging in vigorous exercise, and extra care should be taken when using it alongside other blood sugar-lowering agents. Seventh, if undergoing surgery or experiencing severe infections or dehydration, this medication should be temporarily discontinued as per the physician's instructions. Eighth, this medication is not to be used in women who are pregnant or breastfeeding, or in children under 18 years of age. Ninth, if severe joint pain or skin blisters occur while taking this medication, a doctor should be informed immediately. Finally, it is important to regularly monitor blood sugar, kidney function, and vitamin B12 levels while using this medication and to quickly consult healthcare personnel if any abnormal symptoms occur.

Serious side effects

Urticaria, angioedema, anaphylaxis, Stevens-Johnson syndrome, rash, cutaneous vasculitis and exfoliative skin diseases, acute pancreatitis, acute renal failure, shortness of breath, unstable angina, severe joint pain, bullous pemphigoid, thrombocytopenia, rhabdomyolysis, acute renal failure, hypoglycemia, lactic acidosis, acute pancreatitis, angioedema

Mild side effects

• Diarrhea
• upper respiratory infection
• headache
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• muscle pain
• limb pain

This medication should be stored in a sealed container to prevent air from entering and kept at room temperature between 1 degree and 30 degrees Celsius. Storing it this way can maintain the medication's effectiveness and prevent degradation.

Appearance

Bright pink oval film-coated tablet

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle