Alpra One Tablet 0.25 mg (Alprazolam)

Adult dose

To achieve maximum benefit, determine the dose individually. The usual daily doses listed below are appropriate for most patients, but higher doses may be required. In such cases, increase the dose gradually to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, administer the lowest effective dose for the shortest possible duration and frequently reassess the need for continued treatment. ○ Adults 1. The initial dose of alprazolam is 0.25-0.5㎎ per dose 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ per dose 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ per day of this medicine orally in 3 divided doses. If increasing the dose, increase gradually to a maximum of 2.4㎎ per day and administer orally in 3-4 divided doses. For elderly patients, the initial dose is 0.4㎎ per dose 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder The initial dose of this medicine is 0.5㎎. Depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎, administered in 3-4 divided doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; an even lower dose may be required.

This medication is a benzodiazepine and is used for treating anxiety and panic disorders due to its sedative effects. Caution must be taken when this medication is taken with narcotics, as it can lead to severe sedation, respiratory depression, coma, or even death. If co-administration with narcotics is unavoidable, it should be used at the lowest effective dose for the shortest duration, and the patient's respiratory status and level of consciousness should be closely monitored. There is a risk of abuse and dependence with this medication, so patients receiving treatment should have their condition regularly monitored. Taking this medication with alcohol or other central nervous system depressants can increase risks; thus, they should never be taken together. This medication should not be administered to patients with allergies to it or those with acute closed-angle glaucoma, severe myasthenia gravis, severe respiratory failure, or severe liver failure. Pregnant women in the later stages of pregnancy or individuals with genetic lactose intolerance should also avoid this medication. Patients with heart disease, liver or kidney dysfunction, brain disorders, elderly patients, and those with moderate respiratory failure should use this medication with caution. This medication can cause drowsiness, decreased concentration, and impaired reflexes; therefore, patients should avoid driving or operating dangerous machinery while taking this medication. Long-term users should regularly undergo liver function tests, blood tests, and urine tests. Abrupt discontinuation or rapid dosage reduction of this medication can lead to withdrawal symptoms such as anxiety, insomnia, muscle cramps, and seizures; thus, it should be tapered slowly. If experiencing depression or suicidal thoughts while taking this medication, patients should consult healthcare professionals immediately. This medication has many drug interactions; thus, those currently taking antifungals, antidepressants, narcotic analgesics, antibiotics, hormonal contraceptives, etc., should inform their doctors and use it cautiously. Pregnant or breastfeeding women should consult healthcare professionals before taking this medication, as it may affect the fetus or newborn. The safety of this medication in children under 18 years has not been established; therefore, it is generally not recommended to administer it. In cases of overdose, severe drowsiness, movement disorders, coma, and respiratory depression may occur, and emergency treatment should be sought immediately. This medication should be stored out of reach of children, kept in its original container, and the expiration date and storage conditions must be adhered to.

• Mild discomfort
• insomnia
• abdominal and muscle cramps
• vomiting
• sweating
• tremors
• convulsions
• excitement
• increased muscle rigidity
• sleep disorders

This medication should be stored in a tightly closed container, as it may be affected by air or light. It is important to store it at a cool temperature between 1°C and 30°C and to avoid direct sunlight.

Appearance

White oval tablet

Package unit

30 tablets/bottle, 100 tablets/bottle