Poglizin Tablet 5 mg (Dapagliflozin Propanediol Hydrate)

Adult dose

For monotherapy and additional combination therapy in type 2 diabetes: Take 10 mg once daily. For initial combination therapy (when used with metformin): Take either 5 mg or 10 mg once daily. For patients with chronic heart failure and chronic kidney disease: Take 10 mg once daily. For special populations (patients with severe liver impairment): Start with a dosage of 5 mg, and if well tolerated, it can be increased to 10 mg. Administration method:

Child dose

The efficacy and safety of this medication in children under 18 years of age have not been established, so it should not be administered.

This medication should not be used in patients who are allergic to the active ingredient or other excipients. It should also not be administered to patients with type 1 diabetes or diabetic ketoacidosis. Patients with lactose intolerance, certain genetic issues, and those undergoing dialysis should also refrain from using this medication. It should be used cautiously in patients with low fluid volume or poor kidney function. This medication may cause side effects such as low blood pressure or changes in kidney function, so these patients should be carefully monitored before and after administration. In patients with significantly impaired kidney function, blood sugar control effectiveness may decrease, necessitating careful attention. Side effects like genital infections, urinary tract infections, hypoglycemia, reduced fluid volume, and diabetic ketoacidosis may occur when taking this medication. Especially women, or patients with a history of previous infections, are at higher risk of infections. There may be a risk of hypoglycemia, so dose adjustments may be needed when used with insulin or sulfonylureas. Pregnant or breastfeeding women are advised not to use this medication, and it should be discontinued immediately if pregnancy is confirmed. Elderly patients or those taking multiple medications should be cautious regarding drug interactions and changes in kidney function. This medication can increase urine output, potentially causing reduced fluid volume or low blood pressure, so fluid status should be checked frequently. In case of overdose, there is no specific antidote, and appropriate treatment should be provided based on symptoms. Finally, during the course of taking this medication, blood sugar and ketone levels should be monitored regularly, and any unusual symptoms should lead to immediate consultation with a healthcare professional.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain of oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, abnormal respiratory symptoms accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Vulvovaginitis
• balanitis and related genital infections
• urinary tract infections
• fungal infections
• hypoglycemia
• thirst
• dizziness
• constipation
• dry mouth
• back pain

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness and safety.

Appearance

Yellow, biconvex, round film-coated tablets

Package unit

28 tablets/box [(14 tablets/PTP×2)]