Poglo 5mg (Dapagliflozin Propanediol Monohydrate)

Adult dose

The recommended dose of this medication for monotherapy and as an adjunct to insulin or other antihyperglycemic agents is 10 mg once daily. For initial combination therapy, it is either 5 mg once daily or 10 mg once daily. There are separate dosage adjustment recommendations based on renal impairment, liver impairment, and elderly patients. This medication can be taken orally at any time of day regardless of food intake, and the tablet should be swallowed whole.

Child dose

The efficacy and safety of dapagliflozin in patients under the age of 18 have not been established. There is no related data available.

This medication should not be used in certain patients. Individuals with allergies to the active ingredient or excipients, patients with type 1 diabetes, those with diabetic ketoacidosis, lactose intolerance, genetic metabolic disorders, and patients undergoing dialysis should not take this medication. Patients with decreased fluid volume or impaired renal function should use this medication cautiously. This medication may lower blood pressure or reduce intravascular fluid volume, leading to risks of hypotension or acute kidney injury. Patients with reduced renal function, elderly patients, and those taking diuretics should exercise more caution, and blood pressure and renal function should be carefully monitored before and after administration. Adverse reactions that may occur when taking this medication include genital infections, urinary tract infections, hypoglycemia, dehydration, diabetic ketoacidosis, and various other abnormalities. Particularly, genital infections may be more common in women and those with a history of past infections, so if any infection symptoms occur, it is essential to consult healthcare professionals immediately. Additionally, this medication may induce diabetic ketoacidosis, so even if blood sugar levels are within normal range, if symptoms of ketoacidosis appear, prompt testing and treatment are necessary. Elderly patients or those with compromised liver function should also be cautious when using this medication and should regularly monitor fluid status and blood pressure changes. This medication may increase the risk of hypoglycemia when used in combination with hypoglycemic agents such as insulin or sulfonylurea, thus dose adjustments of such medications may be necessary. It is recommended that women who are pregnant or breastfeeding do not use this medication and if pregnancy is confirmed, they should stop taking it immediately. The safety and effectiveness of this medication for pediatric patients have not been established, and there is no related data available. In case of overdose, there is no specific antidote available, so it is crucial to receive treatment according to the symptoms and follow healthcare professionals' instructions. Finally, this medication does not significantly affect the ability to drive or operate machinery; however, caution is advised for combined use with other medications due to the risk of hypoglycemia.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/conjunctival mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, vision abnormalities, numbness, urination

Mild side effects

• Vulvovaginitis
• balanitis
• urinary tract infections
• fungal infections
• hypoglycemia
• dry mouth
• dizziness
• constipation
• back pain
• dysuria

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is best to store the medication at room temperature between 1°C and 30°C. This way, the medication's effectiveness and safety can be maintained.

Appearance

Yellow, biconvex, round film-coated tablet

Package unit

30 tablets/bottle, 90 tablets/bottle