Dapagliflozin and Sitagliptin Tablets 10/100 mg

Adult dosage

Sitagliptin 100 mg and Dapagliflozin 10 mg, taken once daily as 1 tablet regardless of meal. The tablet should be swallowed whole.

This medication may cause severe allergic reactions due to the Sitagliptin component; if an allergic reaction is suspected, discontinue use immediately and consult a doctor. This medication can cause severe side effects such as acute pancreatitis, marked by inflammation of the pancreas, so if symptoms such as abdominal pain, nausea, or vomiting occur during use, notify healthcare personnel immediately. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and in patients undergoing dialysis. In patients with decreased fluid volume or renal function issues, this medication may cause symptomatic hypotension or worsen renal function, so renal function and fluid status should be carefully assessed before and during use. This medication may increase the risk of genital and urinary infections, so rapid treatment should be sought if infection symptoms develop. As there is a risk of hypoglycemia, blood glucose levels must be carefully monitored and dosing adjusted if used in conjunction with insulin or sulfonylureas. Elderly patients are at higher risk for renal function decline and decreased fluid volume; hence, more caution is needed when taking this medication, and regular monitoring of renal function is recommended. Pregnant or lactating women should avoid using this medication, and it should be discontinued immediately if pregnancy is confirmed. If abnormal symptoms such as skin blisters, rash, or severe joint pain occur during use, notify a doctor immediately. In the case of overdose, no specific antidote is available, so appropriate treatment should be administered based on symptoms. While this medication does not greatly affect driving or machine operation, caution is advised as hypoglycemic symptoms may occur. The safety and efficacy of this medication in children have not been established, so it is advised not to administer it to patients under 18 years of age.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucous membranes, difficulty breathing or shortness of breath, asthma attack, respiratory abnormalities with cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, lightning-like headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination.

Mild side effects

• Headache
• dizziness
• nausea
• diarrhea
• constipation
• dry mouth
• back pain
• dysuria
• polyuria
• nocturia

This medication must be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. Proper storage will help maintain the effectiveness and safety of the medication for a prolonged period.

Appearance

Beige oval film-coated tablets

Package unit

30 tablets/box [(10 tablets/PTP X 3)]