Posidime Sustained Release Tablet 10/500 mg

Adult dose

This medication is generally administered once daily with the evening meal. The maximum dosage is once daily dapagliflozin 10 mg/sustained release metformin 2000 mg, administered as 2 tablets of 5 mg/1000 mg. When using as initial therapy, the recommended starting dosage is once daily 5 mg/500 mg or 10 mg/500 mg, 1 tablet. This medication should be swallowed whole and should never be crushed, cut, or chewed.

This medication is used to help control blood sugar in treating diabetes. It can rarely cause a dangerous condition called lactic acidosis, so patients with poor kidney function or severe infections, dehydration, etc. should not use it. Moreover, caution is needed when used in conjunction with insulin or other hypoglycemic agents, as this may lead to symptoms of hypoglycemia. Patients with moderate to severe renal impairment, those scheduled for acute illness or surgery, hepatically impaired patients, pregnant women, or nursing mothers should not use this medication. This medication should be carefully administered to patients with reduced fluid volume or risk of hypotension, and fluid status and kidney function must be evaluated prior to administration. During use, symptoms of hypoglycemia, lactic acidosis, signs of infection, etc. should be closely observed, and if abnormal symptoms occur, immediate consultation with healthcare professionals is required. This medication may increase the risk of genital and urinary infections, necessitating appropriate treatment if infection symptoms appear. Vitamin B12 levels may decrease, so regular blood tests may be needed for long-term use. Alcohol may increase the risk of side effects from this medication; therefore, excessive drinking should be avoided during administration. This medication may affect certain test results, and when assessing blood sugar control, other tests should be used. Elderly patients or those with impaired kidney function should have dosage adjustments and kidney function monitoring prioritized. Pregnant women and nursing mothers should not use this medication and should discontinue use immediately upon confirmation of pregnancy. In case of overdose, immediate medical attention is required, and dialysis may be beneficial in cases of poor kidney function. This medication does not exert significant effects on driving or operating machinery; however, caution is advised as dizziness and other symptoms may occur. Store out of reach of children and keep in the original container to prevent safety accidents and degradation of quality.

Serious side effects

Severe lactic acidosis, severe hypoglycemia, severe allergic reactions (hypersensitivity), acute kidney injury, lactic acidosis, ketoacidosis, urosepsis, pyelonephritis, acute cholecystitis, Guillain-Barré syndrome, atrial fibrillation, severe edema, severe skin reactions (severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes), serious neurological symptoms (headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis), difficulty breathing

Mild side effects

Hypoglycemia, reduced fluid volume, dry mouth, dizziness, constipation, dry mouth, back pain, dysuria, polyuria, nocturia, vulvar itching, genital itching, elevated hematocrit, reduced renal creatinine clearance at the beginning of treatment, dyslipidemia, elevated serum creatinine at the beginning of treatment, elevated blood urea, weight loss, diarrhea, nausea/vomiting, decreased Vitamin B12/deficiency, upper abdominal pain, dyspepsia, abdominal discomfort, abdominal pain, gastric ulcer,

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, and it is best kept at room temperature between 1 to 30 degrees Celsius. Maintaining this condition helps to retain the effectiveness of the medication for a longer time.

Appearance

Pink rectangular sustained release film-coated tablet

Package unit

30 tablets/box[(6 tablets/PTP)X5], 30 tablets/bottle