DapaPlus Extended Release Tablet 10/500 Milligrams

Adult dose

This medication is generally administered once daily with the evening meal. The maximum dosage is one daily dose of 10 mg dapagliflozin / 2000 mg extended-release metformin, and the administration is two tablets of 5 mg/1000 mg. In cases of initial therapy, one tablet of 5 mg/500 mg or 10 mg/500 mg is taken once daily. To alleviate gastrointestinal side effects of metformin, the dosage is adjusted gradually. Metformin

This medication is used for diabetes treatment and helps to control blood sugar. Before taking this medication, it is essential to verify that kidney function is normal. This medication should not be used in patients with significantly impaired kidney function, and caution is required in cases of reduced kidney function. This medication can rarely cause serious metabolic complications, such as lactic acidosis, so immediate consultation with a doctor is advised if symptoms like sudden fatigue, muscle pain, difficulty breathing, or abdominal pain occur. Additionally, the risk of hypoglycemia may increase when used in conjunction with insulin or sulfonylureas, necessitating close monitoring of blood sugar changes and dosage adjustments as needed. This medication should not be administered to patients with acute conditions that may affect kidney function, such as dehydration, severe infections, or acute myocardial infarction. Before and after examinations using radiological iodine contrast agents, the administration of this medication should be temporarily suspended, and it should only be restarted once normal kidney function is confirmed. Pregnant or potentially pregnant women and nursing mothers should not take this medication and should discontinue it immediately if they are currently taking it. This medication contains lactose, so patients with certain genetic disorders should not take it. In elderly patients, kidney function decline is common, so kidney function should be regularly monitored and treatment should start at a minimum dose. While taking this medication, there is a risk of genital and urinary tract infections, so immediate treatment is required if symptoms of infection appear. Fluid volume reduction or symptoms of low blood pressure may occur, so it is essential for elderly patients or those taking diuretics to closely monitor blood pressure and fluid status. Vitamin B12 levels may decrease, so regular checks of vitamin B12 levels are recommended for long-term usage. Excessive alcohol intake may increase the risk of side effects from this medication, so alcohol should be avoided while taking it. This medication should be temporarily suspended for a certain period before and after surgery, and it should be resumed only after confirming that kidney function is normal post-surgery. During the administration of this medication, there may be failures in blood sugar control or abnormal symptoms, so regular blood sugar checks and consultations with a doctor are important. In the case of overdose, medical assistance should be sought immediately, and while the toxicity of this medication is generally mild, the risk may vary depending on kidney function. While taking this medication, dizziness and other symptoms may occur during driving or operating machinery, so caution is necessary. Finally, this medication should be stored out of reach of children and kept in its original container to prevent misuse or degradation of quality.

Serious side effects

Lactic acidosis, severe hypoglycemia, severe edema, fluid volume depletion, low blood pressure, diabetic ketoacidosis, ketosis, urosepsis, pyelonephritis, acute kidney injury, kidney dysfunction, severe allergic reactions, severe skin reactions, severe neurological symptoms, liver abnormalities (jaundice), perineal necrosis, Guillain-Barré syndrome, bacterial pneumonia, sialadenitis, neurological impairment (Guillain-Barré syndrome, facial paralysis), atrial fibrillation, acute cholecystitis, severe rash

Mild side effects

• Vulvovaginitis
• balanitis
• genital infections
• urinary tract infections
• fungal infections
• hypoglycemia
• dry mouth
• dizziness
• constipation
• dry mouth

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. The storage temperature should be maintained between 1 and 30 degrees Celsius. This helps preserve the medication's efficacy and prevents degradation.

Appearance

Pink biconvex oval extended-release film-coated tablet

Package unit

30 tablets/box [6 tablets/PTP x 5]