Polmindapaserbongjeong 10/1000 milligrams

Adult dose

This medication is generally administered once daily with the evening meal. The maximum dosage is once daily dapagliflozin 10mg/sustained-release metformin 2000mg, which is taken as 2 tablets of 5mg/1000mg. For patients with no previous experience of diabetes medication therapy, the initial regimen is to take 1 tablet once daily of 5mg/500mg or 10mg/500mg. To reduce gastrointestinal side effects of metformin, the dosage should be gradually increased.

This medication can very rarely cause a serious condition called lactic acidosis, so caution is required regarding this. When used with other diabetes medications, there is a risk of hypoglycemia, so caution is advised. It should not be administered to patients with moderate to severe renal impairment or those with dehydration, severe infections, or cardiovascular issues. Pregnant or nursing women and patients with genetic issues such as lactose intolerance should not use this medication. Patients with reduced fluid volume or renal impairment should exercise caution when using this medication, as there may be a risk of blood pressure reduction or deterioration of kidney function, requiring regular monitoring. During treatment with this medication, side effects such as genital infections, urinary tract infections, hypoglycemia, reduced fluid volume, renal dysfunction, etc., may occur, so if symptoms arise, it is crucial to consult healthcare professionals immediately. Furthermore, this medication can lower vitamin B12 levels, so checking vitamin B12 status during long-term use is advised. Excessive alcohol consumption may increase the risk of side effects from this medication. Before surgery or diagnostic tests using iodinated contrast media, this medication should be stopped for a certain period, and it should be resumed only after confirming normal kidney function. Elderly patients are at increased risk of kidney function deterioration and reduced fluid volume, thus requiring dosage adjustments and regular kidney function assessments when using this medication. Caution is also advised for dizziness when operating vehicles or machinery during treatment with this medication. Finally, this medication should be kept out of reach of children and stored in its original container for safety.

Serious side effects

• Lactic acidosis
• severe hypoglycemia
• severe skin reactions
• respiratory distress
• ketoacidosis
• urinary sepsis
• pyelonephritis
• acute kidney injury
• renal dysfunction
• severe edema

Mild side effects

Vulvitis, balanitis and related genital infections, urinary tract infections, fungal infections, hypoglycemia, reduced fluid volume, thirst, dizziness, constipation, dry mouth, back pain, dysuria, polyuria, nocturia, vulvar itching, genital itching, elevated hematocrit, reduced renal creatinine clearance at the start of treatment, dyslipidemia, elevated serum creatinine at the start of treatment, elevated blood urea, weight loss, diarrhea, nausea/vomiting, vitamin B

This medication must be stored in a tightly sealed container to avoid exposure to air or moisture. It is important to maintain storage temperatures between 1 and 30 degrees Celsius to ensure the medication's effectiveness.

Appearance

Yellow, biconvex, oval, sustained-release film-coated tablet

Package unit

30 tablets/box [(6 tablets/PTP x 5)]