Tapagyn Plus Sustained Release Tablet 10/1000mg

Adult dose

This medication is generally administered once daily with the evening meal. The maximum dosage is once daily dapagliflozin 10mg/sustained-release metformin 2000mg. The recommended starting dose for initial therapy is 5mg/500mg or 10mg/500mg once daily. The dosage is adjusted gradually to reduce gastrointestinal side effects of metformin. For patients undergoing prior metformin therapy, the dapagliflozin recommended dose is once daily 10mg and the dosing of this medication should be closely aligned with the therapeutic dose of metformin that was being taken.

This medication is used to treat diabetes and helps to control blood sugar levels. During treatment with this medication, very rarely, a serious condition known as lactic acidosis may occur, so caution is required. Lactic acidosis can lead to an excessive accumulation of lactic acid in the body, resulting in a dangerous condition, and can sometimes be life-threatening. Additionally, when taken with other diabetes medications such as insulin or sulfonylureas, hypoglycemic symptoms may occur, thus blood sugar levels should be closely monitored. Patients with impaired kidney function, dehydration, severe infections, or heart problems should not take this medication. Use of this drug is prohibited in patients with severe impairment of kidney function. If surgery is imminent or if there are plans for tests using iodine contrast agents, this medication should be temporarily discontinued for a period of time and only resumed after confirming that kidney function has returned to normal. Pregnant or nursing women should not take this medication, nor should patients with specific genetic disorders such as lactose intolerance. This medication may cause side effects such as reduced fluid volume, low blood pressure, and changes in kidney function; therefore, particularly in elderly patients or those with weak kidney function, it's essential to consult with a doctor before taking it and to undergo regular kidney function tests. During treatment, there may be occurrences of genital infections or urinary tract infections, so if any symptoms of infection appear, medical professionals should be notified immediately. This medication may also lower vitamin B12 levels, so if taken for an extended period, it is recommended to check vitamin B12 levels through blood tests. Excessive alcohol intake may increase the risk of side effects from this medication and should be avoided. During treatment, be alert for hypoglycemic symptoms, and if dizziness or weakness occurs, consult a doctor immediately. Finally, this medication has not been established as safe and effective for children, so it is not used in this population. It is important to consult with a physician or pharmacist before taking this medication to verify the appropriate usage and precautions corresponding to individual health conditions.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in oral/eye mucous membranes, shortness of breath or difficulty breathing, asthma attack, abnormal breathing accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

Dizziness, constipation, dry mouth, back pain, painful urination, polyuria, nocturia, vulvar itching, genital itching, increased hematocrit, dyslipidemia, increased serum creatinine, increased serum urea, weight loss, hypoglycemia (when used with sulfonylureas or insulin), infection symptoms (vulvovaginitis, balanitis, fungal infection, urinary tract infection, nasopharyngitis, pharyngitis, adenoviral conjunctivitis, herpes zoster, bacterial pneumonia, pneumonia)

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, at a room temperature between 1 to 30 degrees Celsius. By storing it this way, the effectiveness of the medication can be maintained for a longer period.

Appearance

Yellow, double convex, oval-shaped sustained-release film-coated tablet

Package unit

30 tablets/bottle