Dapagliflozin Propanediol Hydrate and Metformin Hydrochloride Extended-Release Tablet 10/500 mg

Adult dose

This medication is generally taken once daily with the evening meal. The maximum dosage is 10 mg of dapagliflozin and 2000 mg of extended-release metformin, administered as 2 tablets of 5 mg/1000 mg. For patients with no previous experience of diabetes medication, the initial regimen is to take one tablet of either 5 mg/500 mg or 10 mg/500 mg once daily. To reduce gastrointestinal side effects of metformin...

This medication is used for diabetes treatment and should not be administered to patients with impaired kidney function or those suffering from certain acute illnesses. This medication can rarely cause a severe side effect known as lactic acidosis, so it is essential to be aware of the symptoms or risk factors associated with lactic acidosis. When used alongside other hypoglycemic agents such as insulin or sulfonylureas, hypoglycemia may occur, so careful monitoring of blood sugar levels is necessary. Use with caution in patients with reduced fluid volume or low blood pressure, elderly patients, and those with compromised kidney function; kidney function and blood pressure should be thoroughly checked before and after administration. This medication may increase the risk of genital and urinary tract infections, so if any infection symptoms arise, seek medical advice immediately. Women who are pregnant or breastfeeding should not use this medication, and women of childbearing potential should consult a healthcare professional before taking this medication. During the course of this medication, excessive alcohol consumption should be avoided, as alcohol may increase the risk of side effects. Vitamin B12 deficiency may occur, so regular monitoring of blood levels of vitamin B12 is advised for long-term use. This medication may cause dizziness when driving or operating machinery, so caution is needed. This medication should be kept out of the reach of children and stored in its original container to prevent degradation or misuse.

Serious side effects

• Lactic acidosis
• severe hypoglycemia
• diabetic ketoacidosis
• urosepsis
• pyelonephritis
• acute kidney injury
• acute cholecystitis
• Guillain-Barré syndrome
• atrial fibrillation
• severe edema

Mild side effects

Hypoglycemia, genital infections (vulvovaginitis, balanitis, etc.), urinary tract infections, fungal infections, decreased fluid volume (dehydration, low blood pressure, etc.), thirst, dizziness, constipation, dry mouth, lower back pain, painful urination, polyuria, nocturia, vulvar itching, genital itching, increased hematocrit, elevated serum creatinine, dyslipidemia, elevated serum urea, weight loss, headache, paresthesia, tremors, epigastric pain, indigestion, abdominal discomfort, diarrhea,

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. The storage temperature should be kept at room temperature, between 1 and 30 degrees Celsius. This helps maintain the medication's effectiveness and safety over time.

Appearance

Pink, double-convex, rectangular extended-release film-coated tablet

Package unit

Bottle packaging - 30 tablets/bottle