Yudapaduo Sustained-Release Tablet 10/500 milligrams

Adult dose

The dosage of this medication should be individualized based on the patient's current treatment regimen, efficacy, and tolerability, without exceeding the maximum recommended dose of 10mg of dapagliflozin and 2000mg of sustained-release metformin. Typically, it is administered once daily with the evening meal. The maximum dose is 10mg of dapagliflozin/2000mg of sustained-release metformin, taken as 2 tablets of 5mg/1000mg. Used as initial therapy.

This medication is used for the treatment of type 2 diabetes. It should not be administered to patients with impaired kidney function or acute illnesses. In particular, using this medication in patients with moderate to severe kidney dysfunction may pose risks. Women who are pregnant or breastfeeding should not take this medication. This medication can cause a rare but serious side effect known as lactic acidosis, so if symptoms of lactic acidosis appear, immediate medical attention should be sought. Additionally, caution is needed when taken with insulin or sulfonylureas due to the risk of hypoglycemia. Regular monitoring of kidney function and fluid status is necessary during use, and there may be symptoms of hypotension or dehydration, which should be taken into account. Genital infections and urinary tract infections may occur, so if related symptoms appear, immediate treatment should be sought. Vitamin B12 levels may decrease, so it is advisable to check the vitamin B12 status when taken long-term. Excessive alcohol intake can increase the risk of side effects of this medication, so it should be avoided. If undergoing surgery or imaging tests with contrast agents, it should be discussed with a doctor about temporarily discontinuing this medication. Elderly patients have a higher likelihood of reduced kidney function, so dosage may need to be adjusted and kidney function should be checked frequently. This medication is not used in children as its safety and efficacy have not been established. Possible side effects include dizziness, dry mouth, constipation, and back pain, and if symptoms are severe, consultation with a physician is necessary. There may be dizziness when driving or operating machinery while taking this medication, so caution is advised.

Serious side effects

• Lactic acidosis
• severe hypoglycemia
• severe edema
• acute kidney injury
• renal impairment
• severe allergic reactions
• ketoacidosis
• urosepsis
• pyelonephritis
• perineal necrosis

Mild side effects

Vulvovaginitis, balanitis and related genital infections, urinary tract infections, fungal infections, hypoglycemia (when used with sulfonylureas or insulin), decreased fluid volume, thirst, dizziness, constipation, dry mouth, back pain, dysuria, polyuria, nocturia, vulvar itching, genital itching, increased hematocrit, initial renal creatinine clearance decrease, dyslipidemia, initial blood creatinine increase, blood urea nitrogen

This medication should be stored in a tightly closed container to protect it from air and moisture, and it is safe to keep it at room temperature between 1 and 30 degrees Celsius. By storing it this way, the medication’s efficacy is maintained and degradation is prevented.

Appearance

Pink, double convex, oblong sustained-release film-coated tablet

Package unit

30 tablets/bottle