Medication info

Jensigamet Sustained-Release Tablet 10/1000mg

Prescription medicationTablet경구
Ingredient · strength
Dapagliflozin Anhydrous Lactose Mixture›15.27mg / 1 tabletMetformin Hydrochloride›1000mg / 1 tablet
Manufacturer / importer
알보젠코리아(주)
Appearance
Yellow, biconvex, oval-shaped sustained-release film-coated tablet
Packaging
30 tablets/box [(6 tablets/PTP*5)], 30 tablets/bottle
Approval status
Active

MFDS item code 202300147 · Approved 2023.01.06

Summary

Main use
Effectiveness in controlling blood sugar levels in type 2 diabetes and preventing cardiovascular events
Who takes it
Adults
Adult dose
The dosage of this medication should be individualized based on the current treatment of the patient, efficacy, and tolerability, without exceeding the maximum recommended dose of dapagliflozin 10mg and sustained-release metformin 2000mg. Generally, it is administered once daily with dinner. The maximum dose is 10mg dapagliflozin/2000mg sustained-release metformin once a day, dosed as 2 tablets of 5mg/1000mg. In initial therapy scenario,

Ingredients

Manufacturer
알보젠코리아(주)

Efficacy & effects

Effectiveness in controlling blood sugar levels in type 2 diabetes and preventing cardiovascular events

  • Type 2 diabetes
  • impaired blood sugar control
  • cardiovascular diseases
  • cardiovascular risk factors
View approved original text

This medication assists in blood sugar control for adult patients with type 2 diabetes who are suitable for combined treatment with dapagliflozin and metformin, alongside diet and exercise. Particularly in patients whose blood sugar is not adequately controlled and have cardiovascular disease or risk factors, caution must be taken by referring to expert guidelines regarding the impact of dapagliflozin on the occurrence of cardiovascular events. Overall, this medication is used to effectively improve blood sugar management in type 2 diabetes patients.

How to take

Adult dose

The dosage of this medication should be individualized based on the current treatment of the patient, efficacy, and tolerability, without exceeding the maximum recommended dose of dapagliflozin 10mg and sustained-release metformin 2000mg. Generally, it is administered once daily with dinner. The maximum dose is 10mg dapagliflozin/2000mg sustained-release metformin once a day, dosed as 2 tablets of 5mg/1000mg. In initial therapy scenario,

Precautions

This medication helps to control blood sugar. Rarely, it may cause a serious condition called lactic acidosis, which can be life-threatening, so caution is required during use. Also, when used with other diabetes medications like insulin or sulfonylureas, hypoglycemia may occur, requiring careful monitoring. Patients with moderate to severe kidney function impairment, dehydration, severe infections, or heart diseases should not take this medication. It should also be temporarily discontinued before and after surgery or radiological examinations, and can only be resumed after confirming normal kidney function. Pregnant or breastfeeding women should not use this medication. This medication can cause decreased fluid volume or low blood pressure; therefore, especially elderly patients or those taking diuretics should regularly check blood pressure and kidney function. Genital infections or urinary tract infections may occur during treatment, so consult a doctor immediately if symptoms arise. Vitamin B12 levels may decrease, so if taken long-term, regular vitamin B12 tests are recommended. Alcohol consumption may increase the risk of side effects from this medication, so it is advisable to avoid it. This medication may interact with other drugs, so inform your doctor or pharmacist if you are taking other medications. In case of overdose, visit a medical facility immediately for appropriate treatment. The safety and efficacy of this medication have not been established in children, so it should not be used in this population. Dizziness may occur during treatment, so caution is advised when driving or operating machinery. Finally, this medication should be stored out of reach of children and kept in the original container to maintain quality.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress with cough and fever, yellowing of the skin or eyes, extreme tiredness, sudden and severe headache, lightning headaches, seizures, confusion of consciousness, visual disturbances, paralysis, significantly reduced urine output

Mild side effects

  • Dizziness
  • constipation
  • dry mouth
  • lumbar pain
  • dysuria
  • polyuria
  • nocturia
  • vulvar itching
  • genital itching
  • elevated hematocrit
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  • increased serum creatinine
  • elevated blood urea
  • weight loss
  • hypoglycemia
  • thirst
  • tendinitis
  • arthralgia
  • myalgia
  • myofascial pain syndrome
  • osteoarthritis
  • osteochondrosis
  • limb pain
  • periarticular inflammation
  • tendinitis
  • trigger finger
  • upper abdominal pain
  • dyspepsia
  • abdominal discomfort
  • diarrhea
  • abdominal pain
  • peptic ulcer
  • irritable bowel syndrome

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a tightly closed container to protect it from air and moisture. It is recommended to keep the storage temperature between 1°C and 30°C at room temperature.

Appearance and packaging

Appearance

Yellow, biconvex, oval-shaped sustained-release film-coated tablet

Package unit

30 tablets/box [(6 tablets/PTP*5)], 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.