Glucita Duo Tablet 50/850 mg

Adult dose

This medication is generally taken twice daily with food, with dosage gradually increasing to reduce gastrointestinal side effects caused by metformin. The initial dosage is determined according to the patient’s current treatment regimen. 1. For patients not currently treated with metformin: Take one tablet of this medication 50/500 mg twice daily, and it can be increased to one tablet of 50/1000 mg twice daily.

This medication contains sitagliptin and metformin, which are both anti-diabetic agents. First, this medication may cause serious allergic reactions in some patients; therefore, if symptoms such as skin rash, hives, or difficulty breathing appear within three months of administration, usage should be stopped immediately, and a doctor should be consulted. Moreover, this medication may induce pancreatitis, so if symptoms such as abdominal pain, vomiting, or nausea arise, immediate medical attention is necessary. The metformin component can cause a rare but life-threatening condition known as lactic acidosis, thus this medication should be discontinued in cases of severe dehydration, infections, heart problems, etc. This medication should not be administered to patients with significantly diminished kidney function, acute heart failure, acute myocardial infarction, severe infections, or dehydration. Additionally, this medication must be discontinued before examinations using iodine contrast agents, and after the kidney function is confirmed normal post-examination, it can be resumed. This medication is not to be used by pregnant or potentially pregnant women, or nursing mothers. While taking this medication, regular checks of kidney function and blood tests are advisable, and periodic monitoring of vitamin B12 levels is also recommended. Due to the risk of hypoglycemia, it is essential to carefully monitor blood sugar changes, especially when used in conjunction with insulin or sulfonylureas. Alcohol consumption may increase the risk of lactic acidosis, so it is best to avoid alcohol while taking this medication. Maintaining regular meals and appropriate exercise while on this medication is important, and if sudden symptoms or adverse reactions occur, immediate consultation with healthcare professionals is necessary.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, severe allergic reactions, rashes, exfoliative skin disease (Stevens-Johnson syndrome), severe rashes with fever, blisters, skin peeling, oral/ocular mucosal pain, severe skin reactions, shortness of breath or difficulty breathing, respiratory distress, asthma attack, respiratory abnormalities accompanied by cough and fever, acute pancreatitis, symptoms of pancreatitis, liver abnormalities (elevated liver enzymes, jaundice), sudden

Mild side effects

• Diarrhea
• upper respiratory tract infection
• headache
• nausea
• vomiting
• abdominal pain
• constipation
• intestinal gas
• indigestion
• weakness

This medication should be stored in a tightly sealed container to prevent exposure to air, and it is best stored at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the effectiveness of the medication over time.

Appearance

Oval film-coated tablet of dark pink color

Package unit

56 tablets/box [(14 tablets/PTP×4)], 30 tablets/bottle, 200 tablets/bottle