Sitagliptin 50/500 mg Tablet

Adult dose

The dosage for this medication is determined based on the individual patient's current treatment regimen, efficacy, and tolerability, without exceeding the maximum daily recommended dosage of sitagliptin 100 mg and metformin 2000 mg for each ingredient. It should be taken twice daily with food, gradually increasing the dosage to minimize gastrointestinal adverse reactions caused by metformin. 1. For patients not receiving metformin: 50/500 mg

This medication contains sitagliptin and metformin, and is primarily used for the treatment of type 2 diabetes. First, severe allergic reactions may occur during the use of this medication, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or lips occur, discontinue use immediately and consult a doctor. There is also a risk of acute pancreatitis, so if abdominal pain, vomiting, or severe abdominal discomfort occurs, notify healthcare professionals immediately. Metformin included in this medication may be dangerous for patients with poor kidney function, so regular kidney function tests should be performed, and this medication should not be taken in cases of significantly reduced kidney function. Particularly, this medication should be avoided in cases of acute conditions such as dehydration, severe infections, heart problems, or acute myocardial infarction, and it may be necessary to discontinue use for a period before any scheduled surgery. It is safe not to take this medication during pregnancy or breast-feeding. This medication can pose a risk of hypoglycemia, so when irregular meals, excessive exercise, or concurrent use with other blood sugar-lowering medications occur, blood sugar levels should be monitored carefully. It is advisable to avoid alcohol consumption during treatment, and patients with poor liver function should also refrain from taking this medication. Gastrointestinal side effects such as diarrhea, nausea, vomiting, abdominal discomfort, and headache may occur, and if symptoms are severe, consult a doctor. Long-term use of this medication may lower vitamin B12 levels, so regular blood tests should be performed and vitamin supplementation may be necessary if needed. Finally, it is important to maintain regular blood sugar tests and kidney function tests during treatment to ensure safety.

Serious side effects

Hives, angioedema, anaphylaxis, exfoliative skin diseases (including Stevens-Johnson syndrome), acute pancreatitis, acute kidney failure, difficulty breathing, unstable angina, severe hypoglycemia, severe joint pain with disabilities, bullous pemphigoid, elevated liver enzymes, liver abnormalities (symptoms related to jaundice specified), lactic acidosis, acute kidney failure, severe swelling with hypertension, severe allergic reactions, serious skin abnormalities

Mild side effects

• Diarrhea
• upper respiratory infection
• headache
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container to prevent air ingress, and it is best kept at room temperature between 1 and 30 degrees Celsius. This will help maintain the effectiveness of the medication and prevent deterioration.

Appearance

Light pink oval film-coated tablets

Package unit

56 tablets/box [(14 tablets/PTP x 4)], 200 tablets/bottle, 30 tablets/bottle