Sitaphol M Tablet 50/850 mg

Adult dose

This medication is generally taken twice a day with food, and the dosage is gradually increased to minimize gastrointestinal side effects caused by metformin. 1. For patients who are not currently treated with metformin: Take this medication at 50/500 mg twice daily, with 1 tablet per dose, and it can be titrated to 50/1000 mg twice daily, with 1 tablet per dose. 2. For patients currently treated with metformin:

This medication contains sitagliptin and metformin, which are used to help control blood sugar levels. Serious allergic reactions may occur while taking this medication; discontinue immediately and consult a physician if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck appear. There is a risk of acute pancreatitis, which is inflammation of the pancreas, so notify healthcare professionals immediately if symptoms such as abdominal pain, nausea, or vomiting occur. Patients with decreased kidney function, severe infections, dehydration, acute myocardial infarction, or heart failure should not take this medication. The medication should be temporarily discontinued before tests using iodine contrast agents, and usage should resume only after kidney function is confirmed to be normal post-examination. Women who are pregnant or may become pregnant, as well as nursing mothers, are advised not to take this medication. There is a risk of hypoglycemia with this medication; caution is especially needed when taken with other antidiabetic agents or insulin, and appropriate measures should be taken immediately if symptoms of hypoglycemia occur. The metformin component can rarely cause a serious metabolic disorder known as lactic acidosis, so immediate medical attention should be sought if sudden fatigue, muscle pain, difficulty breathing, or abdominal pain occur during treatment. Patients with impaired liver function or excessive alcohol consumption should exercise caution when using this medication due to increased risks. While taking this medication, regular blood tests and kidney function tests should be performed, and vitamin B12 levels should be monitored periodically. Patients scheduled for surgery should discontinue this medication 48 hours prior to surgery and resume only after confirming that kidney function has returned to normal following the procedure. The safety and efficacy of this medication have not been established in children under 18 years of age and its use is not recommended. In elderly patients, kidney function may decline, so dose adjustments and regular kidney function monitoring are necessary. In case of overdose, immediate hospital treatment should be sought, and the sitagliptin component may be partially removed through hemodialysis. Alcohol consumption should be avoided while taking this medication, as the risk of lactic acidosis may be increased when taken with alcohol. This medication may interact with other drugs, so it is essential to inform healthcare providers of any other medications being taken.

Serious side effects

Hives, angioedema, anaphylaxis, cutaneous vasculitis, severe cutaneous adverse reactions including Stevens-Johnson syndrome, acute pancreatitis (including fatal/non-fatal hemorrhagic or necrotizing pancreatitis), acute renal failure (sometimes requiring dialysis), dyspnea, worsening kidney function due to acute myocardial infarction, cardiovascular collapse (shock), sepsis, severe hypoglycemia (including confusion, seizures), severe edema, edema with hypertension

Mild side effects

• Headache
• upper respiratory tract infection
• nasopharyngitis
• diarrhea
• nausea
• vomiting
• abdominal pain
• constipation
• weakness
• pruritus

This medication should be stored in a sealed container to prevent exposure to air or moisture, and kept at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's efficacy over time.

Appearance

Dark pink oval film-coated tablet

Package unit

56 tablets/box[(14 tablets/PTP×4)], 200 tablets/bottle, 30 tablets/bottle