Medication info
Durion Extended Release Tablet (Bepotastine Besilate)

Durion Extended Release Tablet (Bepotastine Besilate)

Prescription medicationTabletOral
Ingredient · strength
Bepotastine Besylate›12.22mg / 1 tablet
Manufacturer / importer
Korea HuTex Pharmaceutical Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 202204559 · Approved 2022.12.21 · Insurance code 649105650

Summary

Main use
Relief of perennial allergic rhinitis, itchy skin (such as eczema), and chronic urticaria
Who takes it
Adults
Adult dose
Adults: Take 1 tablet once daily after a meal.

Ingredients

Manufacturer
Korea HuTex Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of perennial allergic rhinitis, itchy skin (such as eczema), and chronic urticaria

  • Perennial allergic rhinitis
  • chronic urticaria
  • pruritus
  • eczema
  • dermatitis
  • skin pruritus
  • urticaria
View approved original text

This medication is used to relieve itching associated with various skin disorders such as perennial allergic rhinitis, chronic urticaria, eczema, and dermatitis.

How to take

Adult dose

Adults: Take 1 tablet once daily after a meal.

Precautions

This medication should not be used in patients who are hypersensitive to its ingredients. Additionally, this medication contains lactose and should not be administered to patients with lactose intolerance or specific genetic issues. Patients with renal or liver dysfunction, as well as the elderly, should use this medication with caution. Taking this medication may cause various side effects such as drowsiness, headache, dizziness, nausea, diarrhea, and skin rashes; if symptoms are severe, consultation with a doctor is advised. Particularly, this medication can cause drowsiness, so caution is needed when driving or operating hazardous machinery. Patients who have been on long-term steroid therapy should gradually reduce steroids when using this medication, and those with diminished renal function should start at a low dose and carefully monitor their condition. For patients with seasonal allergic rhinitis, it is advisable to start and discontinue use at appropriate times according to the season. If no effect is observed, it is preferable not to continue use for a long period. Like other antihistamines, this medication should not be taken with alcohol. Pregnant women, women who may become pregnant, and breastfeeding women are advised not to use this medication; if absolutely necessary, careful consideration and consultation with a doctor is advised. The safety of this medication in children has not been established, so caution is needed for use in pediatric populations. Elderly patients need careful dosing as this medication is primarily excreted through the kidneys, posing a risk for increased serum concentration. This medication may affect allergy tests, so it is advisable to stop taking it before any testing. Finally, it is important to store this medication out of reach of children and not to transfer it to other containers to maintain safety and quality.

Side effects

  • Drowsiness
  • lethargy
  • headache
  • heavy feeling
  • dizziness
  • dry mouth
  • dry mouth mucosa
  • glossitis
  • nausea
  • vomiting
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  • stomach pain
  • discomfort in the upper abdomen
  • diarrhea
  • fluctuation in white blood cell count
  • eosinophilia
  • increased AST
  • increased ALT
  • increased r-GTP
  • increased LDH
  • increased total bilirubin
  • urine protein
  • urine glucose
  • urine hematuria
  • urine urobilinogen
  • rash
  • hypersensitivity reaction with swelling
  • nasopharyngitis
  • upper abdominal pain
  • increased serum bilirubin
  • detection of white blood cells in urine
  • lymphadenitis
  • cervical stenosis
  • nasal dryness
  • indigestion
  • urticaria
  • thirst
  • abdominal discomfort
  • facial edema
  • increased SGOT
  • palpitations
  • facial flushing
  • bitter taste
  • sensory decline
  • bruising
  • tremors
  • constipation
  • folliculitis
  • peripheral edema
  • generalized edema
  • erythema
  • pruritus
  • frequent urination
  • peripheral cold sensation

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or humidity, so it should be kept in a tightly sealed container. The storage temperature should be maintained between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.