Hypervent Extended-release Tablets 90 mg (Diltiazem Hydrochloride)

Adult dosage

(Oral: extended-release capsules) 1. Adults: The usual dose is 180㎎ of diltiazem hydrochloride orally once daily. The dose may be increased to 360㎎ per dose depending on symptoms. 2. Elderly patients and patients with hepatic or renal impairment: The initial dose is 90-120㎎ once daily. Monitor the heart rate during treatment; do not increase the dose if it falls to 50 beats or fewer. The dose may be adjusted as appropriate according to age and symptoms. (Oral: extended-release tablets 30㎎) Adults: Administer 30-60㎎ of diltiazem hydrochloride orally per dose, 3 times daily. The dose may be adjusted as appropriate according to age and symptoms. (Oral: extended-release tablets 90㎎) Adults: Administer 90㎎ of diltiazem hydrochloride orally per dose, twice daily. If necessary, the dose may be increased to 90-180㎎ per dose. The dose may be adjusted as appropriate according to age and symptoms. (Injection) Dissolve this medicine in at least 5㎖ of normal saline or glucose injection solution and administer as follows. 1. Tachyarrhythmia (supraventricular) Adults: Slowly inject 10㎎ of diltiazem hydrochloride intravenously over about 3 minutes as a single dose. 2. Emergency treatment of abnormal hypertension during surgery ① Intravenous bolus injection Adults: Slowly inject 10㎎ intravenously over about 1 minute as a single dose. ② Intravenous infusion Adults: Infuse 5-15㎍ per ㎏ of body weight intravenously over 1 minute. After lowering the blood pressure to the target level, adjust the infusion rate while monitoring blood pressure. 3. Hypertensive emergency (hypertensive crisis) Adults: Infuse 5-15㎍ per ㎏ of body weight intravenously over 1 minute. After lowering the blood pressure to the target level, adjust the infusion rate while monitoring blood pressure. The dose may be adjusted as appropriate according to age and symptoms.

This medication should not be used in patients with cardiac function problems. Particularly, individuals with severe heart failure or abnormal heart rhythms may experience worsening of symptoms when taking this medication. Patients with very low blood pressure or in shock, those allergic to this medication, and those with acute myocardial infarction or pulmonary congestion should also avoid using it. Women who are pregnant or may become pregnant should not take this medication. This medication may cause heart rhythm problems if taken with certain other medications, so co-administration should be avoided. Patients with severely impaired liver or kidney function and those with some cardiac conduction disorders should use this medication with caution, closely monitoring symptoms. While taking this medication, various side effects such as headache, constipation, cough, edema, dyspepsia, dizziness, skin rash, difficulty breathing, and erectile dysfunction may occur; if any unusual symptoms develop, consult medical personnel immediately. Abruptly discontinuing calcium channel blockers may worsen symptoms, so dose reduction should be done gradually under a physician's supervision. It is important to regularly monitor the condition through electrocardiogram tests as this medication can affect heart rate and blood pressure. This medication is primarily metabolized in the liver and excreted through the kidneys and bile, so those with impaired liver or kidney function should be particularly careful. Due to the potential for lowering blood pressure, caution is needed when driving or working at heights. Patients with bronchial asthma or respiratory hypersensitivity may experience worsening respiratory symptoms while on this medication, so monitoring is necessary. This medication can interact with several drugs, so if you are taking other medications, be sure to inform your doctor or pharmacist. Pregnant or breastfeeding women are advised not to take this medication, and if necessary, breastfeeding should be discontinued. Safety and efficacy in children have not been sufficiently confirmed, so caution should be exercised in their use. In cases of overdose, severe hypotension, heart rhythm disturbances, and kidney damage may occur; immediate medical treatment should be sought. If in capsule form, do not open or chew the capsule; swallow it whole.

• Rhinitis
• headache
• pharyngitis
• constipation
• increased cough
• influenza symptoms
• peripheral edema
• myalgia
• diarrhea
• vomiting

This medication is sensitive to air and humidity, so it must be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius to safely preserve the medication's effectiveness.

Appearance

Round extended-release tablet, white or off-white

Package unit

30 tablets/bottle, 500 tablets/bottle