Tralin Tablet 25 mg (Sertraline Hydrochloride)

Adult dosage

Depression and obsessive-compulsive disorder: Start with an initial dose of 50 mg once daily by mouth. The maintenance dose is 50-100 mg daily, and if the effect is insufficient, it can be increased by 50 mg to a maximum of 200 mg daily. Panic disorder, post-traumatic stress disorder, social anxiety disorder: Start with 25 mg once daily and increase to 50 mg after one week. For therapeutic effect, doses of 50-200 mg once daily may be required.

Children's dosage

For patients aged 6-12 with obsessive-compulsive disorder, the initial dose is 25 mg once daily; for patients aged 13-17, the initial dose is 50 mg once daily. If there is no response, the daily dose can be increased to a maximum of 200 mg.

This medication may increase the risk of suicidal thoughts and behavior in young people with depression or psychiatric disorders, so physicians should carefully evaluate the need for treatment and the associated risks. During treatment, patients and their families should closely monitor for changes in abnormal behavior, including suicidal tendencies, aggression, and anger. Serious side effects such as serotonin syndrome or neuroleptic malignant syndrome may occur, so if these symptoms are suspected, immediate consultation with healthcare personnel is necessary. This drug should not be combined with certain other medications, particularly MAO inhibitors, as life-threatening side effects can occur when combined. Patients with moderate or severe liver impairment, those with an allergy to this medication, or patients on certain medications should not be prescribed this drug. Patients with epilepsy or mild liver impairment should be carefully monitored for a risk of seizures and increased drug concentration while taking this medication. Patients with angle-closure glaucoma or a history of glaucoma should be cautious as this medication can dilate pupils, increasing the risk of elevated intraocular pressure. This medication can cause various side effects such as drowsiness, dizziness, headache, insomnia, anxiety, changes in appetite, and also poses a risk of heart rhythm abnormalities or bleeding, making it crucial to report any unusual symptoms immediately. During pregnancy, this medication may affect the fetus, so women of childbearing potential should consult healthcare providers and use appropriate contraception. Breastfeeding women should be cautious as this medication may pass into breast milk. The safety and efficacy of this medication in children and adolescents have not been established, except for some indications, so it should be used with caution. Discontinuing this medication suddenly may result in withdrawal symptoms; therefore, discuss gradually reducing the dose with a doctor. Caution is needed when driving or operating machinery, especially when taken with other sedatives. Interactions with other medications may occur during treatment, so inform healthcare providers of all medications being taken and undergo regular monitoring. Severe side effects can manifest in cases of overdose, so strictly adhere to the prescribed dosage and seek immediate medical attention if in doubt. This medication should be stored safely out of reach of children and should not be transferred to another container arbitrarily.

Serious side effects

Leukopenia, thrombocytopenia, hypersensitivity reactions, anaphylaxis-like reactions, abnormal secretion of antidiuretic hormone, hyperprolactinemia, hyponatremia, coma, serotonin syndrome, Torsade de Pointes, cerebral vasoconstriction, eosinophilic pneumonia, pulmonary hypertension, gastrointestinal bleeding, pancreatitis, liver damage, toxic epidermal necrolysis, Stevens-Johnson syndrome, angioedema, exfoliative dermatitis, photosensitive skin reactions, rhabdomyolysis, dysphagia, hematuria, urinary incontinence

Mild side effects

• Decreased appetite
• increased appetite
• hypoglycemia
• hyperglycemia
• insomnia
• depressive symptoms
• decreased libido
• restlessness
• anxiety
• hallucinations

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. Moreover, it is advisable to keep it at a temperature between 1 to 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle