Posidism Extended-release Tablets 5/500 mg

Adult dose

This medication is generally administered once daily with dinner. The maximum dosage is 10 mg of dapagliflozin and 2000 mg of extended-release metformin once daily, taken as two tablets of 5 mg/1000 mg. The recommended starting dose for initial therapy is one tablet of 5 mg/500 mg or 10 mg/500 mg once daily. To reduce gastrointestinal side effects from metformin, dosage should be adjusted gradually.

This medication helps control blood sugar levels. However, it can rarely cause a dangerous condition called lactic acidosis, so caution is required. When taken in conjunction with other diabetes medications, hypoglycemia may occur, so care should be taken. Patients with impaired kidney function, dehydration, serious infections, heart disease, or other specific health conditions should not take this medication. Pregnant or breastfeeding women should also avoid using this medication. Patients with fluid deficiency or weakened kidney function should consult a doctor before taking this medication and should periodically check blood pressure and kidney function during treatment. When taken with insulin or insulin-secretagogues, dosage adjustments may be necessary to reduce the risk of hypoglycemia. This medication may increase the risk of genital and urinary infections, so if symptoms of infection occur, immediate consultation with healthcare professionals is advised. During treatment, vitamin B12 levels may decrease, so it is recommended to have regular blood tests if necessary. Alcohol consumption may increase the risk of lactic acidosis, so excessive alcohol should be avoided during treatment with this medication. When undergoing certain medical procedures such as surgery or radiological examinations, this medication should be temporarily discontinued, and treatment should resume only after confirming normal kidney function. Elderly patients commonly experience decreased kidney function, so the dosage of this medication should be carefully adjusted, and kidney function should be monitored regularly. In case of overdose, immediate contact with a medical institution for appropriate treatment is required, and this medication can be removed through dialysis. This medication has not established safety and efficacy in children, so it should not be used by them. Lastly, dizziness may occur when driving or operating machinery during the use of this medication, so caution is advised.

Serious side effects

Lactic acidosis, ketoacidosis, urinary sepsis, pyelonephritis, acute kidney injury, kidney failure, Guillain-Barré syndrome, atrial fibrillation, acute cholecystitis, severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness), severe skin adverse reactions (severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes), respiratory problems (breathlessness or difficulty breathing, asthma attacks, cough and发)

Mild side effects

• Genital infection
• urinary infection
• hypoglycemia
• decreased fluid volume
• thirst
• dizziness
• constipation
• dry mouth
• back pain
• dysuria

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it is recommended to keep it at room temperature, between 1 degree and 30 degrees Celsius.

Appearance

Orange, double convex, egg-shaped film-coated tablets

Package unit

30 tablets per bottle