Ilyang Dapagliflozin Sustained-release Tablet 10/500 mg

Adult dose

This medication is generally administered once daily with the evening meal. The maximum dosage is 10 mg of dapagliflozin and 2000 mg of sustained-release metformin once daily. Dosage should be individualized based on the patient’s treatment regimen, efficacy, and tolerability to not exceed the maximum recommended dosage. The recommended starting dose during initial therapy is 1 tablet of 5 mg/500 mg or 10 mg/500 mg once daily. The tablet should be swallowed whole.

This medication is used to treat diabetes and helps control blood glucose levels. Caution is advised as it may pose risks for patients with decreased kidney function or acute kidney injury. This medication should not be administered to patients with severe infections, dehydration, cardiovascular issues, or liver dysfunction. Pregnant or breastfeeding women should also avoid using this medication. When used with other diabetes treatments, the risk of hypoglycemia may increase, hence dose adjustments may be required when combined with insulin or sulfonylureas. Rare side effects such as lactic acidosis can occur during use, so if symptoms such as fatigue, muscle pain, difficulty breathing, or abdominal discomfort appear, immediate medical attention should be sought. This medication may increase the risk of genital and urinary infections, so prompt treatment is necessary if infection symptoms develop. During the course of this medication, there may be a risk of decreased fluid volume or hypotension, so it is important to regularly monitor for dehydration symptoms or changes in blood pressure. Elderly patients or those with renal impairment should have adjusted dosages and regular kidney function tests are necessary. Before undergoing surgery or radiologic examinations with contrast media, this medication should be temporarily discontinued, and use should resume only after kidney function is confirmed to be normal post-examination. In the case of overdose, appropriate symptomatic treatment is necessary, and for the metformin component, dialysis may be helpful. This medication does not significantly affect the ability to drive or operate machinery; however, caution is necessary as dizziness may occur. Lastly, this medication should be stored out of the reach of children and must be kept in its original container to prevent degradation of quality.

Serious side effects

Lactic acidosis, severe hypoglycemia, severe allergic reactions (hypersensitivity), acute kidney injury and renal dysfunction, severe edema and urinary problems, diabetic ketoacidosis, urosepsis and pyelonephritis, acute cholecystitis, Guillain-Barré syndrome, atrial fibrillation, perineal necrosis, rash (including severe skin reactions), sudden and very severe headache, headaches, altered consciousness, visual disturbances, paralysis, breathing difficulties, asthma attacks, cough + fever

Mild side effects

Vulvitis, balanitis, and related genital infections, urinary tract infections, fungal infections, hypoglycemia (when used with sulfonylureas or insulin), decreased fluid volume (dehydration, hypovolemia, hypotension), dry mouth, dizziness, constipation, back pain, dysuria, polyuria, nocturia, vulvar itching, genital itching, dyslipidemia, elevated blood urea, elevated serum creatinine, increased blood glucose, headache, paresthesia, tremors,

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained between 1 degree and 30 degrees Celsius to ensure its effectiveness for a long period of time.

Appearance

Pink, double convex, egg-shaped film-coated tablet

Package unit

30 tablets/bottle