Medication info

DUORICH Sustained-release Tablet 5/500 mg

Prescription medicationTablet경구
Ingredient · strength
Dapagliflozin citric acid›7.35mg / 1 tabletMetformin Hydrochloride›500mg / 1 tablet
Manufacturer / importer
풍림무약(주)
Appearance
Orange, oval-shaped, film-coated tablets with a double convex surface
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 202204057 · Approved 2022.11.10

Summary

Main use
Effect on blood sugar control in type 2 diabetes and prevention of cardiovascular events
Who takes it
Adults
Adult dose
This medication is generally administered once daily with dinner. The maximum dosage is dapagliflozin 10 mg/metformin sustained-release 2000 mg once daily, taking 2 tablets of 5 mg/1000 mg. For those with no prior experience of diabetes medication treatment, the initial regimen is to take 1 tablet of 5 mg/500 mg or 10 mg/500 mg once daily. To reduce gastrointestinal side effects of metformin,

Ingredients

Manufacturer
풍림무약(주)

Efficacy & effects

Effect on blood sugar control in type 2 diabetes and prevention of cardiovascular events

  • Type 2 diabetes
  • impaired blood sugar control
  • cardiovascular diseases
  • cardiovascular risk factors
View approved original text

This medication helps improve blood sugar control in patients with type 2 diabetes through the combined administration of dapagliflozin and metformin. It is particularly effective when used alongside dietary management and exercise therapy. Furthermore, for patients with cardiovascular disease or risk factors, it is advisable to refer to a healthcare professional's guidance regarding potential cardiovascular events. In summary, this medication is used as an adjunct to diet and exercise to improve blood sugar levels in patients with type 2 diabetes.

How to take

Adult dose

This medication is generally administered once daily with dinner. The maximum dosage is dapagliflozin 10 mg/metformin sustained-release 2000 mg once daily, taking 2 tablets of 5 mg/1000 mg. For those with no prior experience of diabetes medication treatment, the initial regimen is to take 1 tablet of 5 mg/500 mg or 10 mg/500 mg once daily. To reduce gastrointestinal side effects of metformin,

Precautions

This medication is used for the treatment of diabetes and should not be administered to patients with impaired kidney function or certain serious diseases. It can very rarely cause a serious side effect known as lactic acidosis, so kidney function tests and symptom monitoring are necessary. Caution should be taken for the risk of hypoglycemia when used together with other diabetes medications such as insulin or sulfonylureas. This medication should be avoided in patients with acute conditions such as dehydration, severe infection, acute myocardial infarction, or sepsis, and should be discontinued for a period before and after surgery. Pregnant or nursing women should not use this medication. Elderly patients or those with weakened kidney function should frequently monitor kidney function and fluid status during the use of this medication, and dosage adjustments may be necessary. This medication may increase the risk of genital infections and urinary tract infections; therefore, any symptoms of infection should prompt immediate consultation with healthcare personnel for treatment. Vitamin B12 deficiency may occur, so checking blood vitamin B12 levels is advisable for prolonged use. Alcohol consumption can increase the risk of side effects from this medication, so excessive drinking should be avoided. If any failure in blood sugar control or abnormal symptoms occur while taking this medication, immediate consultation with a doctor is required. In case of overdose, immediate medical attention is necessary, and dialysis treatment may be required in certain cases. Dizziness or similar symptoms may occur while driving or operating machinery, so caution is needed. Keep this medication out of reach of children and store it in its original container to maintain quality.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, difficulty breathing or shortness of breath, asthma attack, cough with fever accompanying respiratory distress, yellowing of the skin or eyes (jaundice), extreme lethargy throughout the body, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

Hypoglycemia, dizziness, constipation, dry mouth, back pain, pain during urination, polyuria, nocturia, vulvar itching, genital itching, increased hematocrit, decreased renal creatinine clearance at the beginning of treatment, dyslipidemia, increased serum creatinine at the beginning of treatment, elevated blood urea, weight loss, tendinitis, joint pain, muscle pain, myofascial pain syndrome, osteoarthritis, osteochondrosis, limb pain, periarticular inflammation, tenosynovitis, trigger finger, chest pain,

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. Additionally, it is best to store it at room temperature, which ranges from 1 to 30 degrees Celsius, without extremes of heat or cold.

Appearance and packaging

Appearance

Orange, oval-shaped, film-coated tablets with a double convex surface

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.