Ramocan Pre-filled Syringe (Ramosetron Hydrochloride)

Adult dosage

Adult: Administer 0.3 mg of Ramosetron Hydrochloride intravenously once daily. If the effect is insufficient, the same dose may be administered additionally, but should not exceed 0.6 mg per day. Adjust dosage according to symptoms.

This medication should not be used in patients with a known allergy to this drug or any of its other components. Caution should be exercised when administering this drug to patients taking other serotonergic medications, such as selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs). During the use of this medication, there may be rare occurrences of serious allergic reactions or symptoms of shock; if symptoms appear, administration should be discontinued immediately, and appropriate treatment should be provided. Cases of seizure-like events have also been reported; thus, caution is needed in patients with a history of seizures. Side effects such as headache, dyspepsia, diarrhea, and liver function abnormalities may occur; if symptoms are severe, patients should consult a physician. This medication is recommended for patients who have undergone chemotherapy that induces severe nausea and vomiting. When taken in combination with serotonergic drugs, a serious side effect known as serotonin syndrome may occur; therefore, patients should be closely monitored when using concurrently. As this medication is metabolized in the liver, caution is necessary as blood levels may increase when taken with certain drugs. Women who are pregnant or may become pregnant should consult their physician carefully regarding the need for this medication; it is advisable to discontinue breastfeeding while on this medication. Safety in pediatric patients has not been sufficiently established, so caution is needed for use in children. Elderly patients may have decreased bodily functions; therefore, careful monitoring is required when administering this medication, and immediate action should be taken if side effects appear. This medication should not be mixed with certain injection solutions, as problems may arise during preparation; it is advisable not to mix it.

Serious side effects

Shock, anaphylactoid symptoms (chest discomfort, breathing difficulties, asthma, hypotension, etc.), seizure-like episodes

Mild side effects

• Headache
• heaviness in the head
• diarrhea
• constipation
• rash
• itching
• redness
• psychological symptoms
• feeling of warmth in the body
• retching

This medication is sensitive to light and should be stored in a dark place. It should also be kept in a sealed container to prevent air ingress, and it is recommended to store it at room temperature, between 1°C and 30°C.

Appearance

A colorless and transparent liquid in a single-use pre-filled syringe.

Package unit

Box - 5 pre-filled syringes/box [2 milliliters/pre-filled syringe x 5], Box - 6 pre-filled syringes/box [2 milliliters/pre-filled syringe x 6]