Medication info
Dimantine Tablet 20 mg (Memantine Hydrochloride)

Dimantine Tablet 20 mg (Memantine Hydrochloride)

Prescription medicationTablet경구
Ingredient · strength
Memantine Hydrochloride›10mg / 1 tablet
Manufacturer / importer
현대약품(주)
Appearance
White oval film-coated tablet
Packaging
100 tablets/bottle, 30 tablets/bottle
Approval status
Active

MFDS item code 202203939 · Approved 2022.10.28 · Insurance code 642004950

Summary

Main use
Treatment of moderate to severe Alzheimer's disease
Who takes it
Adults
Adult dose
This medication should be taken once daily by mouth, at the same time each day. If necessary, it may be administered twice daily. Dosage increase: The maximum daily dose is 20 mg, and to minimize the risk of adverse effects, it should be increased weekly by 5 mg over the first three weeks. First week (days 1-7): 5 mg daily for 7 days. Second week (days 8-14): 10 mg daily for 7 days.

Ingredients

Manufacturer
현대약품(주)

Efficacy & effects

Treatment of moderate to severe Alzheimer's disease

  • Alzheimer's disease
View approved original text

This medication is used for the treatment of moderate to severe stage Alzheimer's disease. It helps improve the decline in memory and cognitive function of patients, thereby enhancing their quality of life in daily activities.

How to take

Adult dose

This medication should be taken once daily by mouth, at the same time each day. If necessary, it may be administered twice daily. Dosage increase: The maximum daily dose is 20 mg, and to minimize the risk of adverse effects, it should be increased weekly by 5 mg over the first three weeks. First week (days 1-7): 5 mg daily for 7 days. Second week (days 8-14): 10 mg daily for 7 days.

Precautions

This medicine should not be used by individuals who are allergic to any of its components. It should also not be administered to patients with severely impaired liver function or significantly decreased kidney function. Since this medication contains lactose, individuals with hereditary disorders that prevent lactose digestion should not take it. Patients with epilepsy or those who have experienced seizures in the past, or individuals predisposed to epilepsy should use this medication with caution. Moreover, simultaneous use with certain medications such as amantadine, ketamine, or dextromethorphan may increase side effects, so it is advisable not to co-administer them. If there are changes in dietary habits that may affect urine acidity or if there are specific kidney disorders, urine status should be monitored carefully. Patients with heart problems or uncontrolled hypertension need to be cautious while using this medication. Taking this medication may result in side effects such as dizziness, headache, constipation, drowsiness, and high blood pressure, and in some patients, hallucinations or psychotic symptoms have been rarely reported. If taken with certain medications, it may interact with them, leading to changes in effectiveness or increased side effects, so it is essential to consult a doctor or pharmacist if taking other medications. Women who are pregnant or may become pregnant should be careful when taking this medication, and breastfeeding women are advised to discontinue breastfeeding while on this medication. It is advisable not to use this medication in children or adolescents under 18 years of age, as safety and efficacy have not been established. In case of overdose, central nervous system and digestive system issues may arise, and immediate medical attention should be sought. This medication can slow down reaction times, so caution should be exercised when driving or operating machinery. Finally, keep this medication out of the reach of children and avoid transferring it to other containers.

Side effects and when to seek care immediately

Serious side effects

Seizures, vascular disorders (venous thrombosis/thromboembolism), shortness of breath, hepatitis, liver function impairment (including elevated liver function test results), central nervous system symptoms (including severe symptoms such as coma, hallucinations, psychotic reactions, seizures, confusion, drowsiness, dizziness, gait disturbances, and visual disturbances)

Mild side effects

  • Dizziness
  • headache
  • constipation
  • drowsiness
  • high blood pressure
  • drug hypersensitivity
  • confusion
  • hallucinations
  • psychotic reactions
  • balance disorder
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  • abnormal gait
  • seizures
  • heart failure
  • venous thrombosis/thromboembolism
  • shortness of breath
  • vomiting
  • pancreatitis
  • elevated liver function test results
  • hepatitis
  • fatigue
  • anxiety
  • aggression
  • stupor
  • loss of consciousness
  • restlessness
  • visual disturbances

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container that allows no air to pass through, at a temperature maintained at room temperature between 1 and 30 degrees Celsius. Storing it this way ensures the stability of the medication's components and allows it to exert its effects properly.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

100 tablets/bottle, 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.