Lepizol Tablets 2 mg (Aripiprazole)

Adult dose

1. Schizophrenia - Recommended initial dose is 10 mg or 15 mg once daily, irrespective of meals. The dose may be adjusted within a range of 10-30 mg daily; however, the dosage should not be increased before 2 weeks necessary to reach a stable state. - Efficacy of maintenance therapy at a daily dosage of 15 mg has been proven through clinical trials for relapses. 2. Treatment of bipolar disorder and related conditions

Child dose

1. Schizophrenia (Adolescents 13-17 years old) - Recommended dose is 10 mg daily, irrespective of meals. - Initial daily dose is 2 mg, which is increased to 5 mg after 2 days and then again to 10 mg after another 2 days.

This medication may increase the risk of suicidal thoughts or behavior in children, adolescents, and young adults with major depressive disorder or other psychiatric disorders. Therefore, a doctor should carefully consider prescription for patients in this age group. Patients of all ages taking this medication should be closely monitored for worsening depression, suicidal tendencies, and abnormal behavior changes. Family members or guardians should carefully observe the patient and consult a doctor immediately if abnormal symptoms are detected. This medication may cause a serious side effect known as Neuroleptic Malignant Syndrome, which can manifest as high fever, muscle rigidity, changes in mental status, and autonomic instability. Immediate medical treatment is required if such symptoms appear. Long-term use may result in tardive dyskinesia, a disorder characterized by involuntary movements. Therefore, the duration of treatment and the dosage should be kept to a minimum, with regular monitoring of the patient's condition. In elderly patients with dementia, the use of this medication may increase the risk of death and cerebrovascular events; therefore, it is not recommended for the treatment of dementia-related psychiatric disorders. Diabetic patients or those at risk of hyperglycemia must regularly check their blood sugar levels during treatment with this medication. Consult healthcare professionals immediately if hyperglycemic symptoms occur. This medication may cause orthostatic hypotension; thus, particular caution is needed for patients with cardiovascular disease or those at high risk of hypotension when taking this medication. Patients with a history of seizures or at high risk of seizures should be closely monitored for potential seizure occurrence when using this medication. This medication may impair judgment and motor skills; therefore, it is advisable to avoid driving or operating dangerous machinery while taking it. The ability to regulate body temperature may be diminished, requiring caution during excessive exercise or exposure to high-temperature environments. This medication may increase the risk of dysphagia and aspiration pneumonia; therefore, particular care should be taken when using it in elderly patients or those with swallowing difficulties. For patients at high risk of suicide, prescribe the minimal effective dose to reduce the risk of overdose, and ensure close supervision of the patient's condition. This medication contains lactose; therefore, patients with lactose intolerance or related genetic disorders should not take this medication. Common side effects that may occur during treatment include nausea, vomiting, constipation, headache, dizziness, insomnia, anxiety, drowsiness, fatigue, weight gain, and extrapyramidal symptoms. If these symptoms are severe or persistent, consult healthcare professionals. Various side effects such as cardiac-related adverse reactions, blood sugar anomalies, muscle rigidity, and akathisia have been reported; thus, regular health monitoring during treatment is essential. If any abnormal symptoms occur while taking this medication, consult a doctor immediately, especially for suicidal thoughts, severe muscle rigidity, seizures, or severe allergic reactions, as immediate treatment is necessary.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain at mucous membranes (mouth/eyes), difficulty or shortness of breath, asthma attack, respiratory abnormalities with coughing and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, urination issues

Mild side effects

• Nausea
• vomiting
• constipation
• headache
• dizziness
• akathisia
• anxiety
• insomnia
• restlessness
• drowsiness

Store this medication in a tightly closed container to protect it from air and moisture. It is advisable to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage can help maintain the efficacy of the medication for a longer period.

Appearance

Green rectangular tablets

Package unit

30 tablets/bottle, 200 tablets/bottle