Teriglmets Tab 20/1000 mg

Adult dose

This medication is generally administered once daily with the evening meal. The 20/1000 mg extended-release tablet is taken once daily, one tablet at a time. For the 10/750 mg or 10/500 mg extended-release tablets, it is taken once daily, two tablets simultaneously. The initial dose is teneligliptin 20 mg once daily combined with the existing metformin dose. The maximum recommended daily dose is teneligliptin 20 mg and extended-release metformin 2000 mg.

This drug helps control blood sugar levels. However, it can rarely lead to a serious condition called lactic acidosis, which is a dangerous state caused by the excessive accumulation of lactic acid in the body. Lactic acidosis can occur more frequently in patients with poor kidney function, heart disease, severe infections, or dehydration. Therefore, patients with moderate or severe renal impairment, acute heart failure, or acute myocardial infarction should not take this drug. Additionally, if iodine contrast media is used for radiological examinations, the drug should be discontinued 48 hours prior to the examination and restarted only after confirming normal kidney function. It is recommended that pregnant women or women of childbearing potential avoid using this medication. Caution is required as the risk of hypoglycemia may increase when taken with insulin or sulfonylurea medications. If sudden dizziness, severe abdominal pain, vomiting, or difficulty breathing occurs during use, prompt consultation with a physician is necessary. Additionally, patients with poor liver function, severe pulmonary disease, or severe malnutrition should use this medication cautiously. Elderly patients may experience decreased kidney function, and regular kidney function tests are recommended, with dosage adjustments made as necessary. Alcohol consumption should be avoided during treatment, and regular blood tests are recommended as vitamin B12 levels may drop. If surgery is performed, the medication should be discontinued 48 hours before the surgery, and recomended to restart only after confirming normal kidney function postoperatively. This drug has not been established for safety and efficacy in children, and should not be used in this population. Lastly, this drug should be kept out of reach of children and should not be transferred to another container.

Serious side effects

Lactic acidosis (severe metabolic acidosis), severe hypoglycemia, liver function disorders (including jaundice), severe allergic reactions (hives, severe swelling, chest tightness, cold sweat, paleness, difficulty breathing), severe skin reactions (severe rash with fever, blisters, skin peeling, mucosal pain in mouth/eyes), respiratory problems (shortness of breath or difficulty breathing, asthma attacks, cough with fever), severe neurological symptoms (sudden and severe symptoms)

Mild side effects

• Hypoglycemia
• constipation
• dizziness
• headache
• fatigue
• musculoskeletal pain
• rash
• itching
• allergic dermatitis
• upper respiratory infection

This medication should be stored in a tightly sealed container to prevent air and moisture intrusion. It is important to maintain storage temperature between 1 degree Celsius and 30 degrees Celsius at room temperature.

Appearance

Pink oval extended-release film-coated tablet

Package unit

30 tablets/bottle