Tenelitin M Extended-release Tablet 20/1000 mg

Adult dose

This medication is generally administered once daily with the evening meal. The 20/1000mg extended-release tablet is taken once daily, 1 tablet at a time. The 10/750mg or 10/500mg extended-release tablets are taken once daily, 2 tablets at the same time. The initial dosage should provide 20mg of teneligliptin once daily and the existing dose of metformin. To maintain the extended-release properties, this medication should not be broken or crushed.

This medication can very rarely cause severe lactic acidosis, so caution is needed for this symptom. Lactic acidosis is a life-threatening condition, and if any unusual symptoms arise, immediate medical attention should be sought. This medication should not be administered to patients with moderate to severe renal impairment, and the renal function should be regularly monitored to ensure it is normal. Patients with impaired renal function may have increased risks of side effects due to drug accumulation in the body. Patients with cardiovascular diseases such as heart failure or acute myocardial infarction, and severely infected or trauma-affected patients should avoid or use this medication with caution. Before undergoing examinations with radiological iodine contrast agents, this medication should be discontinued at least 48 hours prior and resumed only after confirming normal kidney function post-exam. It is safer to avoid this medication in pregnant women, women who could become pregnant, and patients with liver dysfunction. Additionally, caution is needed for undernourished, starving, or weak patients. When used with insulin or sulfonylurea medications, the risk of hypoglycemia may increase, so care should be taken to be aware of hypoglycemic symptoms and to take quick action such as consuming glucose if symptoms appear. In case of abdominal pain, vomiting, or severe constipation indicating intestinal obstruction, discontinue the medication immediately and seek medical advice. This medication should not be given to patients who may experience hypoxic states due to liver dysfunction, pulmonary dysfunction, excessive alcohol consumption, dehydration, diarrhea, or vomiting. Elderly patients may have a risk of renal impairment, so dosage adjustments and regular renal function tests should be performed. During administration of this medication, vitamin B12 levels may decrease, so it is advisable to check vitamin B12 levels through regular blood tests. Skin conditions such as bullous pemphigoid may occur, so if any blisters or skin irritations develop, the doctor should be informed immediately. The safety and efficacy of this medication in children have not been established, so it is not used in pediatric patients. Alcohol consumption should be avoided during treatment, and the medication should be discontinued in cases of acute or chronic alcohol poisoning. The effectiveness of blood sugar control may vary depending on other medications used in conjunction with this one, so proper management in consultation with a doctor is necessary when taking other diabetes medications or drugs together.

Serious side effects

• Urticaria
• severe swelling (edema)
• cold sweat
• chest tightness
• difficulty breathing
• severe rash with fever
• blistering
• skin peeling
• pain in mucous membranes of mouth/eyes
• severe allergic reaction

Mild side effects

• Hypoglycemia
• constipation
• dizziness
• abdominal distension
• abdominal discomfort
• nausea
• abdominal pain
• bloating
• stomatitis
• gastric polyps

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is best to maintain the storage temperature between 1°C and 30°C.

Appearance

Pink oval-shaped extended-release film-coated tablet

Package unit

30 tablets/bottle