Tenediar Sustained-Release Tablet 10/500 mg

Adult dose

This medication is generally administered once a day, with dinner, and the dosage is adjusted gradually to minimize gastrointestinal side effects associated with Metformin. Patients taking the 20/1000 mg sustained-release tablet should take it once a day, one tablet at a time. Patients taking the 10/750 mg or 10/500 mg sustained-release tablets should take it once a day, two tablets simultaneously. For patients who cannot achieve sufficient blood sugar control with Metformin monotherapy, the initial dose of this medication should provide Teneligliptin 20 mg once daily along with the existing dosage of Metformin. For patients switching from a combined regimen of Teneligliptin and Metformin, the dosage can start based on the existing dosages of both medications. When converting from immediate-release Metformin to sustained-release formulations, blood sugar control should be closely monitored and adjustments made appropriately. When administered in conjunction with sulfonylureas, it may be advisable to consider reducing the dosage of sulfonylureas to minimize the risk of hypoglycemia. The maximum recommended daily dose is Teneligliptin 20 mg and sustained-release Metformin 2000 mg. The safety and efficacy of this medication have not specifically been evaluated in patients switching from other antidiabetic medications. Because it may cause changes in blood sugar control, any modifications in treatment for patients with type 2 diabetes should be made under careful monitoring. To maintain the sustained-release properties, the tablet should be swallowed whole and not divided, crushed, chewed, or broken.

This medication is used for the treatment of diabetes and aids in controlling blood sugar levels. However, it can very rarely cause a metabolic complication called lactic acidosis, which can pose a life-threatening risk. It should not be administered to patients with impaired kidney function, heart failure, liver disease, severe infections, etc., and administration should be suspended for a certain period before and after surgery. Additionally, caution should be exercised when used in conjunction with insulin or sulfonylurea medications as the risk of hypoglycemia may increase. Patients should consult a doctor immediately if symptoms of hypoglycemia or suspected lactic acidosis appear during treatment. Regular function tests are required since this medication can affect liver and kidney functions, and special care is needed for the elderly or those with reduced kidney function. Alcohol consumption should be avoided during treatment as it can increase the risk of lactic acidosis. It is advised that pregnant women, women who may become pregnant, and nursing mothers do not take this medication. Safety in children and adolescents has not been established, so it should not be used. In case of overdose, patients should visit a hospital immediately for appropriate treatment, and in severe cases, hemodialysis may be required. Caution should be taken regarding interactions with other medications during the use of this medication, especially as there is an increased risk of hypoglycemia when combined with other blood-sugar-lowering medications. Patients should pay attention to any changes in symptoms while taking medications and consult healthcare professionals immediately if any unusual symptoms occur.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, cold sweats, tightness in the chest, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, liver dysfunction, jaundice, sudden and severe headache, confusion, visual disturbances, paralysis, seizures, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough and fever, severe systemic swelling with increased blood pressure, markedly reduced urine output.

Mild side effects

• Hypoglycemia
• constipation
• dizziness
• tremors
• headaches
• weakness
• hunger
• fatigue
• facial swelling
• diarrhea

This medication should be stored in a tightly closed container to prevent exposure to air or moisture and kept at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a longer duration.

Appearance

Orange egg-shaped sustained-release film-coated tablet

Package unit

30 tablets/bottle