Tenelia Duo Sustained-release Tablet 10/500 mg

Adult dose

This medication is generally administered once daily with the evening meal. The 20/1000 mg sustained-release tablet is taken once daily, 1 tablet at a time. Patients taking the 10/750 mg or 10/500 mg sustained-release tablets should take 1 dose of 2 tablets at once once daily. The maximum recommended daily dosage is 20 mg of Teneligliptin and 2000 mg of sustained-release Metformin. To maintain the sustained-release properties, this medication

This medication contains Metformin and Teneligliptin and is primarily used for the treatment of type 2 diabetes. It can very rarely cause a serious metabolic complication known as lactic acidosis, which can be fatal and requires special caution. Lactic acidosis is associated with decreased kidney function, heart disease, liver disease, severe infections, dehydration, and excessive alcohol intake, so patients with these conditions or risks should not use this medication. It should also not be administered to patients with moderate to severe impairment of kidney function, congestive heart failure, acute myocardial infarction, sepsis, or liver dysfunction. If undergoing tests that use iodine contrast agents, this medication should be discontinued 48 hours prior to the test, and resumed only after confirming normal kidney function. This medication should be avoided in pregnant women or women who may become pregnant, as well as in patients with severe infections, severe trauma, or those scheduled for surgery. The risk of hypoglycemia may increase when this medication is taken with insulin or sulfonylurea medications, so patients with irregular meal intake or heavy exercise need to be especially careful. Patients with a history of heart disease related to QT interval prolongation should also be administered cautiously. While taking this medication, patients should be well aware of the symptoms of hypoglycemia, and if such symptoms occur, immediate intake of sugar and appropriate measures should be taken. Though rare, serious side effects such as liver dysfunction, acute pancreatitis, interstitial pneumonia, and blistering skin diseases may occur, and patients should consult healthcare professionals if any abnormal symptoms appear. Additionally, this medication may interact with other medications that can affect kidney function, so patients must inform healthcare professionals of any other medications they are taking. Elderly patients are at a higher risk for decreased kidney function and should have regular kidney function tests and may require dosage adjustments. In case of overdose, appropriate treatment such as gastrointestinal decontamination and ECG monitoring should be undertaken, and in severe cases, dialysis may be necessary. This medication should be kept out of reach of children, and it is advisable not to change the container arbitrarily. It is recommended that pregnant or nursing mothers do not use this medication, and nursing mothers should discuss with healthcare providers whether to stop breastfeeding or discontinue the medication. The safety and efficacy of this medication in pediatric patients have not been established, so it is not used in children.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, difficulty breathing or shortness of breath, asthma attack, respiratory abnormalities with cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, lightning headache, seizure, confusion, visual disturbances, paralysis, urination

Mild side effects

• Hypoglycemia
• constipation
• dizziness
• headache
• abdominal bloating
• abdominal discomfort
• nausea
• abdominal pain
• flatulence
• stomatitis

This medication should be stored in a tightly closed container to protect it from air and moisture. The storage temperature is best maintained between 1 to 30 degrees Celsius at room temperature to preserve the drug's effectiveness and safety for a long time.

Appearance

Orange oval sustained-release film-coated tablet

Package unit

30 tablets/bottle