Doxycycline 50 mg Tablets (Doxycycline Hydrate)

Adult dose

Adults: The initial dose is 100 mg (potency) of doxycycline orally every 12 hours. The maintenance dose is 100 mg (potency) per day in 1 ∼ 2 divided doses. For severe infections, administer the initial dose every 12 hours. This medicine should be continued for an additional 24 ∼ 48 hours after symptoms subside and fever resolves. For streptococcal infections, continue treatment for at least 10 days to prevent the development of rheumatic fever or glomerulonephritis. Adjust the dose as appropriate according to age and symptoms.

Child dose

Adolescents aged 12 years and older: For those weighing 45 kg or less, administer an initial dose of 4 mg (potency)/kg of body weight per day orally in 2 divided doses. The maintenance dose is 2 mg (potency)/kg of body weight per day, administered in 1 ∼ 2 divided doses. Adolescents aged 12 years and older: For those weighing more than 45 kg, administer the dose corresponding to the adult dose.

This drug can cause serious gastrointestinal diseases such as diarrhea and colitis due to Clostridium difficile, so if diarrhea occurs after taking it, notify your healthcare provider immediately. Also, during the use of this medication, severe skin rashes, mucosal damage, or systemic symptoms associated with skin reactions may occur. If these symptoms appear, discontinue the use of the drug immediately and seek treatment at a hospital. This medication should not be used in patients with hypersensitivity, pregnant or breastfeeding women, and children under 12 years of age, as it poses a risk of causing tooth discoloration and bone growth issues, particularly in children. Patients with severely impaired kidney or liver function, and those with certain muscle disorders should use this medication with caution, and dosage adjustments or regular monitoring may be necessary. During treatment, care should be taken to avoid excessive sun exposure, and if symptoms of skin reddening or burn-like reactions appear, discontinue the medication and consult a physician. This drug may interact with other medications, so if you are currently taking other drugs, be sure to inform your healthcare provider, especially when taking anticoagulants, oral contraceptives, antacids, and certain antibiotics. When taking the medication, it should be taken with plenty of water while sitting or standing, and it should be avoided before bedtime as this may increase the risk of esophageal irritation or ulceration. In case of overdose, severe symptoms such as vomiting, nausea, liver and kidney damage may occur, so seek appropriate treatment at a medical institution immediately. For prolonged use of this drug, regular checks of liver, kidney, and blood functions are recommended to detect any abnormalities. Finally, special caution should be exercised when administering this drug to children, elderly patients, and those in poor overall health, and careful observation for the occurrence of side effects is necessary.

Diarrhea, colitis, exfoliative dermatitis, erythema multiforme, mucocutaneous syndrome, toxic epidermal necrolysis, drug reactions accompanied by eosinophilia and systemic symptoms, hemolytic anemia, neutropenia, thrombocytopenia, hypersensitivity, anaphylactic shock, angioedema, exacerbation of systemic lupus erythematosus, pericarditis, serum sickness, hypotension, dyspnea, tachycardia, peripheral edema, urticaria, thyroid microscopic brown discoloration, decreased appetite, headache, benign intracranial hypertension, papilledema, tinnitus, flushing, nausea, vomiting, dyspepsia, pancreatitis, membranous colitis, esophageal ulcer, esophagitis, enterocolitis, perianal genital inflammation lesion, dysphagia, abdominal pain, glossitis, tooth discoloration, hepatotoxicity, hepatitis, liver function abnormality, photosensitivity reaction, rash, exfoliative dermatitis, photo-induced nail and toenail detachment, arthralgia, myalgia, increased BUN, anemia, decreased granulocytes, atypical lymphocytes, decreased lymphocytes, lymphadenopathy, coagulopathy, anaphylactic reaction, fever, paresthesia, anxiety, restlessness, severe colitis with blood in stool, loose stool, stomatitis, sore throat, black hairy tongue, hoarseness, jaundice, nail and toenail detachment, change in nail color, fixed drug eruption, arthritis, kidney damage, interstitial nephritis, acute kidney failure, oliguria, hematuria, visual disturbances, optic disc edema, decreased and loss of smell and taste, vitamin K deficiency, vitamin B complex deficiency symptoms, facial tongue and laryngeal edema, yellow urine, decreased urine sugar, liver and kidney parenchymal damage, esophagitis, esophageal ulcer, anaphylactic reaction

This medication should be stored in a tightly sealed container to protect it from exposure to air or light. Additionally, it should be stored at room temperature, maintaining a temperature between 1 to 30 degrees.

Appearance

Pink round tablet

Package unit

30 tablets/bottle, 300 tablets/bottle