Daparon Duo Extended-Release Tablets 10/1000 mg

Adult dose

This medication is generally administered once daily with the evening meal. The maximum dosage is 10 mg of dapagliflozin/2000 mg of extended-release metformin, dosed as 2 tablets of 5 mg/1000 mg. If there is no prior experience with diabetes medication, the initial therapy involves taking 1 tablet of 5 mg/500 mg or 10 mg/500 mg once daily. To reduce gastrointestinal side effects of metformin, dosage should be increased gradually.

This medication is used for the treatment of diabetes and helps manage blood sugar levels. However, it should not be used in patients with impaired kidney function, acute infections, or severe heart diseases. Additionally, it is safer not to administer it to pregnant or breastfeeding women. This medication can rarely cause a serious condition called lactic acidosis, so if symptoms such as muscle pain, difficulty breathing, or weakness occur, consult a doctor immediately. When used in combination with insulin or other diabetes medications, there is a risk of hypoglycemia, so caution is necessary. Patients with reduced fluid volume or low blood pressure, especially the elderly or those using diuretics, must ensure kidney function and fluid status are confirmed before starting this medication. Regular monitoring for symptoms of low blood pressure or changes in kidney function is needed during use. This medication may increase the risk of genital and urinary infections, requiring prompt treatment if infection symptoms occur. Also, vitamin B12 deficiency may develop, so it is advisable to check vitamin B12 levels during long-term use. Excessive alcohol should be avoided, and it is recommended to discontinue the medication for a certain period before surgery or X-ray examinations. Weight loss and increased urine output may occur during the use of this medication, so these should be monitored. In case of overdose, seek immediate medical attention.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attacks, respiratory anomalies accompanied by cough + fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, consciousness disturbance, visual disturbances, paralysis, urination changes

Mild side effects

• Vulvovaginitis
• balanitis and related genital infections
• urinary infections
• fungal infections
• hypoglycemia
• thirst
• dizziness
• constipation
• dry mouth
• low back pain

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is best to keep the storage temperature between 1 degree and 30 degrees Celsius at room temperature.

Appearance

Yellow, bilaterally convex, oval-shaped extended-release film-coated tablet

Package unit

30 tablets/bottle