Samsung Ibuprofen Premix Injection

Adult dosage

Used as an adjunct therapy for moderate to severe pain control with narcotic analgesics (morphine) at a dosage of 400 mg to 800 mg intravenously as needed at intervals of 6 hours. The maximum daily dose can be up to 3200 mg, and infusion time must be at least 30 minutes. For antipyretic purposes, 400 mg can be administered intravenously at intervals of 4-6 hours as needed. Depending on the patient's condition, after an initial 400 mg dose, additional doses may be administered at 4-hour intervals.

Children's dosage

From 6 months to under 12 years: Administer intravenously starting at 10 mg/kg (maximum 400 mg) as needed at intervals of 4-6 hours, with a minimum infusion time of 10 minutes. Maximum daily dose of 40 mg/kg or

This drug should be used with caution in patients with cardiovascular diseases or risk factors, as there is a higher risk of serious cardiovascular issues such as myocardial infarction and stroke. In addition, serious gastrointestinal side effects such as gastrointestinal bleeding or ulcers may occur, so the elderly or long-term users should be particularly careful. This medication should not be taken by individuals with a history of gastrointestinal ulcers or bleeding, severe liver or kidney impairment, severe hypertension, or allergies to any component of this drug. Those with bronchial asthma or who have experienced hypersensitivity reactions to aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) should not use this medication. During late pregnancy, it may pose risks to the fetus, so it should be avoided. Patients undergoing cancer treatment with high-dose methotrexate should also refrain from using this drug. Patients with blood disorders or tendencies to bleed, those with impaired liver or kidney function, the elderly, pregnant women, and nursing mothers should use this drug with caution. If serious allergic reactions or unusual symptoms such as nausea, vomiting, headache, skin rash, or respiratory difficulty occur during treatment, medical consultation should be sought immediately. In particular, patients with hypertension, heart failure, or impaired kidney function should closely monitor their blood pressure and fluid status when taking this drug. This drug should not be used in conjunction with other nonsteroidal anti-inflammatory drugs, and it is recommended to take the lowest effective dose for the shortest duration. Adverse interactions may occur when taken with aspirin, anticoagulants, ACE inhibitors, diuretics, lithium, and methotrexate, so it is paramount to inform healthcare professionals and take necessary precautions. During pregnancy, especially after 20 weeks, it may affect fetal kidney function, so amniotic fluid status should be monitored. In breastfeeding women, this medication may pass into breast milk, so considering discontinuation of breastfeeding or the medication itself is advised. Safety and effectiveness have not been established for children under 6 months, and the elderly may have decreased bodily functions, necessitating dose adjustment and close monitoring. In cases of overdose, serious symptoms such as dizziness, nausea, vomiting, kidney failure, respiratory difficulties, and hypotension may occur, and immediate medical attention should be sought if symptoms are suspected.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in mouth/eyes mucous membranes, shortness of breath or difficulty breathing, asthma attacks, cough with fever and respiratory abnormalities, jaundice (yellowing of skin or eyes), profound malaise, sudden and intense headache, thunderclap headache, seizures, altered consciousness, vision abnormalities, paralysis, and urinary issues

Mild side effects

• Nausea
• vomiting
• bloating
• headache
• hemolysis
• drowsiness
• indigestion
• diarrhea
• wound hemolysis
• abdominal discomfort

This medication should be stored in a sealed container to protect it from air and moisture. It is important to maintain a room temperature between 1 degree and 30 degrees.

Appearance

A colorless or light yellow liquid filled in a colorless transparent plastic container for injection.

Package unit

100 milliliters/vial, 200 milliliters/vial