Poglin 10 mg (Dapagliflozin Propanediol Hydrate)

Adult dose

The recommended dose of this drug is 10 mg taken once daily for monotherapy and additional combination therapy with other antidiabetic medications such as insulin. In initial combination therapy with metformin, it can be given as 5 mg once daily or 10 mg once daily. This drug can be taken orally at any time of the day, regardless of food intake. The tablet should be swallowed whole.

Child dose

The efficacy and safety of dapagliflozin in children under 18 years of age have not been established.

This drug should not be used in patients with allergies to the main ingredient or excipients. It should not be administered to patients with type 1 diabetes or diabetic ketoacidosis. It is also not suitable for patients with lactose intolerance or certain genetic metabolic disorders. It should not be used in patients receiving dialysis. Use with caution in patients with volume depletion or renal function problems. This drug may lower blood pressure or cause temporary changes in renal function, necessitating caution. Patients with impaired renal function, the elderly, and those taking diuretics should closely monitor their fluid status and renal function. During treatment with this drug, there may be occurrences of genital infections and urinary tract infections, so if related symptoms appear, immediate consultation with healthcare professionals is necessary. There is a risk of hypoglycemia, so dosage adjustments may be needed when used with insulin or sulfonylureas. If dehydration or hypotension symptoms occur, it is advisable to temporarily stop taking this drug and consult a healthcare professional. Severe metabolic abnormalities known as diabetic ketoacidosis may occur, so immediate examination is needed if symptoms such as vomiting, abdominal pain, or difficulty breathing arise. It is safest for women who are pregnant or breastfeeding not to use this drug, and if pregnancy is confirmed, it should be discontinued. Elderly patients have a higher risk of decreased renal function and reduced fluid volume, so caution should be exercised. This drug may increase urination, so patients with bladder-related diseases should consider the possibility of condition worsening when using it. In case of overdose, as there are no specific antidotes, appropriate treatment should be undertaken based on symptoms, and attention should be paid to dehydration or hypotension symptoms. During treatment with this drug, caution should be exercised for hypoglycemia symptoms while driving or operating machinery, especially when taken with insulin or sulfonylureas. The safety and efficacy of this drug have not been established in children, so it is not used in that population. When storing the drug, keep it out of the reach of children and store it in its original container to maintain quality.

Serious side effects

• Urticaria
• Severe swelling (edema)
• Chest tightness
• Difficulty breathing
• Cold sweat
• Paleness
• Severe rash with fever
• Blisters
• Skin peeling
• Pain in oral/ocular mucosa

Mild side effects

• Vulvovaginitis, balanitis, and related genital infections
• Urinary tract infections
• Hypoglycemia
• Reduced fluid volume (including dehydration, hypovolemia, hypotension)
• Dizziness
• Constipation
• Dry mouth
• Low back pain
• Dysuria
• Polyuria

This drug may be sensitive to air or moisture, so it should be stored in a sealed container. It is best to maintain storage temperatures between 1 degree and 30 degrees Celsius at room temperature. This way, the drug's efficacy can be preserved for a long time.

Appearance

Yellow, biconvex, diamond-shaped film-coated tablet

Package unit

PTP - 28 tablets/box [28 tablets (7 tablets/PTP x 4)], bottle - 30 tablets/bottle