Atenel M Extended Release 20/1000 mg

Adult dose

This medication is typically administered once daily with the evening meal, with the 20/1000 mg extended-release tablet being taken as one tablet once daily. The 10/750 mg or 10/500 mg extended-release tablets should be taken as two tablets at once once daily. The initial dose should be started with Teneligliptin 20 mg once daily and existing dosing for Metformin. The maximum recommended daily dose is Teneligliptin 20 mg and extended-release Metformin 2000 mg.

This drug is used for the treatment of diabetes and has the effect of lowering blood glucose. There is a very rare risk of developing a serious condition called lactic acidosis during the use of this medication, so caution is warranted. Lactic acidosis is a dangerous condition characterized by an elevated level of lactate in the blood and acidosis, and it is more likely to occur in patients with decreased renal function or those with severe infections, heart issues, etc. Additionally, hypoglycemic symptoms may occur when used in conjunction with insulin or sulfonylureas, so blood glucose should be checked frequently, and patients should be well-informed about the symptoms of low blood sugar. Patients with moderate to severe renal impairment, severe heart failure, hepatic dysfunction, acute infections or severe trauma, or those in a very poor nutritional state should not use this medication. Patients scheduled to undergo tests using radiologic iodinated contrast media should discontinue taking this medication 48 hours prior to the test and resume only after renal function is confirmed to be normal post-examination. Women who are pregnant or may become pregnant, as well as nursing mothers, should ideally not use this medication. This drug can cause side effects such as gastrointestinal disturbances, hepatic function abnormalities, hypoglycemia, acute pancreatitis, skin rash, etc., and patients should consult a physician immediately if any unusual symptoms occur. Furthermore, it is important to regularly monitor renal function and blood tests during the course of treatment with this medication. Alcohol consumption may increase the risk of lactic acidosis, so patients should avoid drinking alcohol while on this medication. Elderly patients may have decreased renal function, so dosage adjustments and regular testing are necessary. This medication may interact with other diabetes treatments, so patients should inform their physician or pharmacist of any other medications they are taking. Patients due to undergo surgery should stop taking this drug 48 hours before the surgery and resume it only after renal function is confirmed to be normal post-surgery. If any severe abdominal pain, persistent vomiting, difficulty breathing, muscle pain, or weakness occurs while taking this medication, the patient should seek medical help immediately. Finally, this medication is not used in children and adolescents as its safety and efficacy have not been established.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, severe rash with high fever, blisters, shedding of skin, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough+fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, vision changes, paralysis, urine

Mild side effects

• Dizziness
• constipation
• abdominal distension
• abdominal discomfort
• nausea
• abdominal pain
• bloating
• stomatitis
• gastric polyps
• colon polyps

This medication should be stored in a tightly sealed container to keep out air, at room temperature between 1 degrees and 30 degrees Celsius. Storing it this way helps maintain the effectiveness of the medication and prevents deterioration.

Appearance

Pink, egg-shaped extended-release film-coated tablet

Package unit

30 tablets/bottle