Glucita Duo Sustained Release Tablet 50/1000 mg

Adult dose

This medication should be taken once daily with dinner to reduce gastrointestinal adverse reactions associated with metformin, gradually increasing the dosage. To maintain its sustained-release properties, this medication should be swallowed whole and not split, crushed, chewed, or broken. For the 100/1000 mg sustained-release tablet, take 1 tablet once daily. For the 50/500 mg sustained-release tablet or the 50/1000 mg sustained-release tablet, take 2 tablets once daily.

This medication is a diabetes treatment containing the components sitagliptin and metformin, and there are several important precautions when taking it. First, allergic reactions may occur while taking this medication; if symptoms such as rash, difficulty breathing, or swelling of the face or neck appear, stop taking it immediately and consult a doctor. Second, there is a risk of pancreatitis, which is inflammation of the pancreas, so if abdominal pain, nausea, or vomiting occurs, seek medical attention immediately. Third, patients with severely reduced kidney function, acute infections, dehydration, or heart problems should not take this medication. Fourth, it is advisable for pregnant women, or women who may become pregnant, and lactating women to avoid using this medication. Fifth, hypoglycemic symptoms may occur, so it is necessary to eat regularly and avoid strenuous exercise or drinking alcohol. Sixth, this medication is not recommended for patients with liver dysfunction, and if there are symptoms of liver dysfunction, it should be discontinued. Seventh, this medication should be temporarily stopped before and after surgery or any examinations requiring contrast agents, and it should be resumed only after confirming that kidney function is normal. Eighth, during treatment with this medication, regular kidney function and blood tests should be conducted, and especially elderly patients need to be more cautious. Ninth, the risk of hypoglycemia may increase when this medication is combined with other hypoglycemic agents or certain medications; therefore, it is essential to consult a doctor when taking medications. Finally, in the case of an overdose, contact a medical institution immediately for appropriate treatment, and this medication can be partially removed through dialysis. If any unusual symptoms occur while taking this medication, inform healthcare personnel immediately and follow their instructions.

Serious side effects

Hives, angioedema, anaphylaxis, Stevens-Johnson syndrome and exfoliative skin disorders, acute pancreatitis, deterioration of renal function and acute renal failure, lactic acidosis, hypoglycemia, severe and debilitating joint pain, bullous pemphigoid, elevated liver enzymes, liver dysfunction (jaundice), acute pancreatitis, acute renal failure, thrombocytopenia, rhabdomyolysis, severe allergic reactions, serious neurological symptoms

Mild side effects

• Diarrhea
• upper respiratory tract infection
• headache
• nausea
• vomiting
• abdominal pain
• constipation
• nasopharyngitis
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. The safest storage temperature is between 1°C and 30°C. It is advisable to avoid places that are too hot or too cold.

Appearance

Bright green, oval-shaped, sustained-release film-coated tablet with a convex surface on both sides

Package unit

28 tablets/bottle, 56 tablets/bottle, 200 tablets/bottle