Teneglib M Sustained-release Tablet 20/1000 mg

Adult dose

This medication is generally administered once daily with evening meals, and the 20/1000 mg sustained-release tablet is taken as 1 tablet once a day. The 10/750 mg or 10/500 mg sustained-release tablets are taken as 2 tablets simultaneously once a day. The initial dosage should provide 20 mg of teneligliptin once daily along with the existing dosage of metformin. The maximum recommended dosage per day is 20 mg of teneligliptin and sustained-release metformin.

This medication can rarely cause a serious metabolic complication called lactic acidosis; therefore, it should not be administered to patients with impaired kidney function or liver dysfunction. The risk of hypoglycemia may increase when this medication is used with other diabetes treatments, so immediate action, such as consuming sugar, is necessary if hypoglycemia symptoms occur. This medication should not be administered to certain patient populations, such as those with moderate or severe impaired kidney function, heart failure, patients at risk for acute renal failure, type 1 diabetes patients, or pregnant women. At least 48 hours before a testing involving radiological iodine contrast materials, this medication should be stopped, and re-administered only after confirming normal kidney function afterwards. Caution should be exercised when administering this medication to patients with liver dysfunction, severe pulmonary dysfunction, serious infections, malnutrition, starvation, frailty, adrenal insufficiency, and administration can be temporarily halted if necessary. Since this medication contains tartrazine, which can cause allergic reactions, patients hypersensitive to this component should be careful. If there are persistent abdominal pain, vomiting, severe constipation, shortness of breath, fever, skin rash, or blisters during use, immediate consultation with a physician is required, as these symptoms may indicate serious side effects. Elderly patients should regularly undergo kidney function tests due to the potential for decreased renal function and should start with the minimum dosage to ensure adequate blood glucose control. It is recommended that pregnant and lactating women do not use this medication, and women who may become pregnant should confirm their pregnancy status before deciding to take the medication. In cases of overdose, immediate visit to a medical institution for appropriate treatment is necessary, as this medication can be removed by hemodialysis. Patients performing hazardous work or driving should use this medication with caution due to the risks of lactic acidosis or hypoglycemia. Additionally, this medication may interact with other drugs, so it is essential to inform the physician or pharmacist about any other medications being taken.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash along with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, cough with accompanying fever and respiratory distress, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headaches, thunderclap headache, seizures, confused consciousness, visual disturbances, paralysis, urination

Mild side effects

• Constipation
• dizziness
• abdominal distension
• abdominal discomfort
• nausea
• abdominal pain
• bloating
• stomatitis
• gastric polyps
• colon polyps

This medication should be stored in a tightly sealed container to prevent air or moisture exposure and kept at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness for a longer time.

Appearance

Pink oval-shaped sustained-release film-coated tablet

Package unit

30 tablets/bottle