Zadium Duo Tablet 5/1000 mg (Empagliflozin, Metformin Hydrochloride)

Adult dose

The recommended dose of this medication is 1 tablet per dose, taken twice a day. The maximum recommended daily dose of empagliflozin is 25 mg, and for metformin it should not exceed 2000 mg. When using metformin alone or in combination with other medications, continue the existing metformin dosage while administering empagliflozin 5 mg twice daily (a total of 10 mg). If tolerance is excellent and additional blood sugar control is needed, empagliflozin

This medication may cause a very dangerous condition called lactic acidosis, so caution is necessary, especially in individuals with impaired kidney function or those with serious infections, dehydration, or heart problems. Patients with allergies to the main ingredients or components of this medication, those with moderate to severe kidney impairment, type 1 diabetes patients, or those with acute metabolic acidosis should not take this medication. Furthermore, when undergoing tests that use iodinated contrast agents, this medication should be discontinued before and after the test and resumed only after kidney function has recovered. There is a risk of hypoglycemia when taken in conjunction with insulin or sulfonylurea medications, so blood sugar levels and symptoms should be closely monitored when using these medications together. Patients with compromised kidney function or elderly individuals should have regular kidney function tests and consider dosage adjustments or discontinuation if necessary. This medication may cause side effects such as urinary infections or genital infections, increased urination, so any related symptoms should be reported to healthcare professionals immediately. It is advisable to avoid alcohol consumption during treatment, and temporary discontinuation may be necessary during acute illnesses or surgeries. Women who are pregnant, may become pregnant, or are breastfeeding should not use this medication due to safety concerns. This medication can lower vitamin B12 levels, so periodic monitoring of vitamin B12 levels is necessary when used for extended periods. Serious side effects, such as lactic acidosis, may occur in cases of overdose, requiring immediate emergency treatment. This medication has not been established as safe or effective for use in children and is not recommended for individuals under the age of 18. Additionally, during use of this medication, care should be taken to prevent wounds on the feet and maintain foot health.

Serious side effects

• Hives
• angioedema
• perineal necrosis
• ketoacidosis
• lactic acidosis
• pyelonephritis
• urosepsis
• liver dysfunction
• hepatitis
• acute kidney injury

Mild side effects

• Urinary infections
• genital infections
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation
• taste abnormalities

This medication should be stored in a tightly sealed container to protect it from exposure to air or moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius to preserve the medication's efficacy over time.

Appearance

A yellow, brownish, oval-shaped, biconvex film-coated tablet

Package unit

60 tablets/box (10 tablets/PTP x 6), 10 tablets/box (10 tablets/PTP x 1), 60 tablets/bottle, 30 tablets/bottle