Empagduo Tablet 5/850 mg

Adult dose

The recommended dose of this medication is 1 tablet once, 2 times a day. The treatment regimen, efficacy, and tolerability of each patient should be considered and should not exceed empagliflozin 25 mg and metformin 2000 mg total daily maximum dose. If blood glucose control is difficult when metformin is used alone or in combination with other drugs, empagliflozin 5 mg should be taken 2 times a day (total 10 mg) along with the existing metformin dosage. If tolerability is good and additional blood glucose control is needed, empagliflozin 25 mg (total daily dose) can be increased.

This medication may cause a rare but serious side effect called severe lactic acidosis, so caution is needed, especially in patients with impaired kidney function or in cases of severe infection or dehydration. Additionally, the risk of hypoglycemia may increase when taken with insulin or sulfonylurea medications, so close monitoring of blood sugar levels is necessary. This medication should not be used in patients with moderate to severe renal impairment, acute cardiac problems or heart failure, acute infections, severe trauma, before or after surgery, and requires dose adjustment according to renal function and regular monitoring of renal function tests. Caution is also required in patients at risk of fluid loss or those with irregular meals or engaging in strenuous exercise. While taking this medication, side effects may occur such as urinary tract infections or genital infections and increased urination; if any abnormal symptoms occur, immediate consultation with healthcare professionals is advised. Moreover, vitamin B12 levels may decrease over time, so regular blood tests are recommended during prolonged use. Pregnant or breastfeeding women should not take this medication, and dosage for the elderly should be adjusted according to renal function. In cases of overdose, hypoglycemia or lactic acidosis may occur, requiring immediate hospital treatment. This medication is not recommended for children or adolescents under 18 years of age. It is important to avoid alcohol while taking this medication, maintain proper hydration, and regularly undergo examinations as directed by a physician.

Serious side effects

• Hives
• angioedema
• necrosis of the perineum
• ketoacidosis
• lactic acidosis
• cerebral infarction
• myocardial infarction
• acute kidney injury
• acute pyelonephritis
• urosepsis

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. The preferred storage temperature is between 1 to 30 degrees Celsius at room temperature. Proper storage will help maintain the effectiveness of the medication for a long time.

Appearance

White film-coated tablets that are convex on both sides with a yellowish tint

Package unit

10 tablets/box [10 tablets/PTPX1], 60 tablets/box [10 tablets/PTPX6], 60 tablets/bottle