Empagliflozin/Metformin Tablet 5/850 mg

Adult dose

The recommended dose of this medication is 1 tablet once or twice a day. The maximum recommended daily dose of empagliflozin is 25 mg, and for metformin, it should not exceed 2000 mg, determined based on each patient's current treatment regimen, efficacy, and tolerability. For patients who cannot achieve adequate blood glucose control with metformin alone or in combination with other medications such as insulin, the recommended dose is 5 mg of empagliflozin twice daily (total daily dose 10 mg).

This drug is used to treat diabetes and contains two components that help control blood sugar. It can cause a rare side effect known as severe lactic acidosis, so special caution should be taken, especially by patients with impaired kidney function or those with heart diseases. Additionally, if taken with other diabetes medications such as insulin or sulfonylureas, there is a risk of hypoglycemia, so dosage adjustments may be necessary when using these medications together. This medication should not be administered to patients with moderate to severe renal impairment or to those in serious conditions such as acute infections, dehydration, heart failure, or acute myocardial infarction. If undergoing tests involving iodinated contrast agents, the medication should be discontinued for a certain period before and after the examination, and can only be resumed once normal kidney function is verified. Women who are pregnant or nursing should not take this medication, and it is not recommended for children or adolescents under the age of 18. This drug may increase the risk of urinary tract infections and genital infections, so any signs of infection should be reported to a healthcare provider immediately. During treatment, kidney function and blood sugar levels should be monitored regularly, and vitamin B12 levels may also need to be checked. Additionally, this medication can cause fluid loss, so elderly patients or those at risk of dehydration should be carefully observed. In cases of overdose, blood dialysis may be required, and the reported side effects of this medication include nausea, vomiting, diarrhea, abdominal pain, hypoglycemia, and liver function abnormalities. Lastly, it is advisable to avoid alcohol consumption while taking this medication, and the decision to continue use during surgery or serious illness should be made in consultation with healthcare providers.

Serious side effects

Hives, severe swelling (edema), lactic acidosis, ketoacidosis, angioedema, perineal necrosis, urosepsis, pyelonephritis, headache (severe headache, thunderclap headache), cerebral infarction, acute kidney injury, jaundice (yellowing of skin or eyes), acute cholecystitis, autoimmune hepatitis, cholelithiasis, severe allergic reactions, severe skin adverse reactions, serious neurological symptoms, difficulty breathing, severe swelling or urination abnormalities,

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This drug may be sensitive to air or moisture, so it should be stored in a sealed container. It is important to maintain storage temperatures between 1 and 30 degrees Celsius at room temperature.

Appearance

White oval film-coated tablets that are convex on both sides with a yellow tint.

Package unit

10 tablets/box [(10 tablets/PTP×1)], 60 tablets/box [(10 tablets/PTP×6)], 60 tablets/bottle