Empadown Duo Tablet 5/500 mg (Empagliflozin, Metformin Hydrochloride)

Adult dose

The recommended dosage for this drug is 1 tablet, taken twice daily. Each patient's current treatment regimen, efficacy, and tolerability should be considered to ensure that the total daily maximum recommended doses of empagliflozin 25 mg and metformin 2000 mg are not exceeded. Patients who cannot achieve adequate blood sugar control with metformin alone or in combination with other medications like insulin are recommended to take empagliflozin 5 mg twice daily (total of 10 mg).

This drug is used for diabetes treatment, where the two components work together to control blood sugar. There is a risk of a rare side effect known as severe lactic acidosis while taking this drug, so if symptoms occur, consult a doctor immediately. Caution is needed when used with other diabetes medications as hypoglycemia may occur. Patients with significantly reduced kidney function or acute kidney issues, severe infections, or congestive heart failure should not use this drug. Before undergoing tests that use iodine contrast agents, this drug should be temporarily discontinued, and it should be resumed only after kidney function is confirmed to be normal. If scheduled for surgery, discontinue this drug 48 hours prior to the procedure and resume only after confirming normal kidney function post-surgery. Those with poor liver function or excessive alcohol intake should be cautious when using this drug. It is safer for women who are pregnant or breastfeeding not to take this drug. Elderly patients or those with reduced kidney function should have regular kidney function tests and may require dosage adjustments. This drug may increase urinary output, so patients at risk of dehydration or hypotension should closely monitor their fluid status. During treatment, symptoms of genital or urinary tract infections may occur, and appropriate treatment should be sought if symptoms arise. Vitamin B12 levels may decrease, so it is advisable to regularly check vitamin B12 levels during long-term use. Hypoglycemic symptoms may occur, especially when taken with other blood sugar-lowering agents, so blood sugar levels should be carefully monitored. In cases of overdose, serious side effects may occur, so the drug should be taken according to the doctor's instructions for accurate dosing. This drug is not recommended for children or teenagers under 18 years of age. Regular consultations with a physician during treatment are necessary, and any unusual symptoms should be reported to healthcare providers immediately. To store this drug safely, keep it out of the reach of children and store it in its original container.

Serious side effects

Hives, angioedema, necrosis of the perineum, ketoacidosis, lactic acidosis, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, yellowing of skin or eyes (jaundice), systemic severe allergic reactions.

Mild side effects

• Hypoglycemia
• urinary tract infections
• genital infections
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This drug may be sensitive to air and moisture and should be stored in a tightly sealed container. It is important to maintain storage temperatures between 1 and 30 degrees Celsius. Proper storage will help ensure the drug's effectiveness.

Appearance

Orange-yellow, oval film-coated tablet with a biconvex shape

Package unit

10 tablets/box [10 tablets/PTP x 1], 60 tablets/box [10 tablets/PTP x 6], 60 tablets/bottle