Utenem Extended Release Tablet 10/500 mg

Adult dose

This medication is generally administered once daily with the evening meal, and the dosage is titrated gradually to reduce gastrointestinal side effects associated with metformin. The 20/1000 mg extended-release tablet is taken as 1 tablet once daily. For patients taking the 10/750 mg or 10/500 mg extended-release tablets, take 2 tablets simultaneously once daily. In patients who cannot achieve adequate blood sugar control using metformin alone, the initial dose of this medication should provide 20 mg of teneligliptin once daily in conjunction with the existing metformin regimen. In patients transitioning from teneligliptin and metformin combination therapy, the dose of this medication can start at the existing doses of teneligliptin and metformin. When converting from immediate-release metformin to extended-release, blood sugar control should be closely monitored, and dose adjustments should be made as appropriate. When used in combination with sulfonylureas, consider reducing the dose of sulfonylureas to minimize the risk of hypoglycemia. The maximum recommended daily dose is 20 mg of teneligliptin and 2000 mg of extended-release metformin. The safety and efficacy of this medication have not been specifically evaluated in patients transitioning from other hypoglycemic agents. Since it can induce changes in blood sugar control, any changes in the treatment of type 2 diabetes should be done under careful monitoring. To maintain the extended-release properties, this medication should not be crushed, split, chewed, or bitten, but should be swallowed whole.

This medicine is used for the treatment of diabetes. It can rarely cause a serious side effect called lactic acidosis, so it should not be administered to patients with impaired kidney function or liver dysfunction to prevent this symptom. Additionally, caution is necessary when taken with insulin or other diabetes medications as hypoglycemia may occur. If planning surgery or experiencing severe infections, trauma, dehydration, etc., this medication should be temporarily stopped. Rarely, side effects such as pancreatitis, interstitial pneumonia, skin rashes, and joint pain may occur, so if any abnormal symptoms arise, consult a doctor immediately. It is recommended that women who are pregnant or may become pregnant, as well as nursing mothers, do not take this medication. Elderly patients should adjust the dosage considering decreased kidney function and undergo regular kidney function tests. It is advisable to avoid alcohol consumption during treatment with this medication, particularly as acute alcohol intoxication may increase the risk of lactic acidosis. Patients taking this medication should fully understand the symptoms of hypoglycemia and how to respond to them. If symptoms of hypoglycemia appear, appropriate measures should be taken immediately. This medication should not be used in children as its safety and efficacy have not been established. Additionally, it is important to consult with a doctor or pharmacist regarding potential interactions with other medications while taking this medicine. In case of overdose, visit the hospital immediately for appropriate treatment, and if necessary, blood dialysis can be used to remove the drug. Lastly, this medication should be stored out of reach of children and should not be transferred to another container.

Serious side effects

Severe allergic reactions (hives, swelling, chest tightness, difficulty breathing, cold sweat, pallor), severe skin reactions (severe rash with fever, blisters, peeling skin, pain in mouth/eyes mucosa), respiratory issues (shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever), liver issues (yellowing of skin or eyes (jaundice), severe fatigue), severe neurological symptoms (sudden

Mild side effects

• Hypoglycemia
• constipation
• dizziness
• abdominal distension
• abdominal discomfort
• nausea
• abdominal pain
• bloating
• stomatitis
• gastric polyps

This medicine should be stored in a tightly sealed container to protect it from air and moisture, ideally at room temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the drug's efficacy and prevent deterioration.

Appearance

Orange egg-shaped extended-release film-coated tablets

Package unit

30 tablets/bottle