Tenel M Sustained-Release Tablets 10/750 mg

Adult dose

The usual dose of this medication is once daily with the evening meal. The 20/1000 mg sustained-release tablet is taken once daily, 1 tablet per dose. The 10/750 mg or 10/500 mg sustained-release tablets are taken once daily, 2 tablets at the same time. The initial dose should provide Teneligliptin 20 mg once daily and the previously prescribed dose of Metformin. To maintain its sustained-release characteristics, do not split, crush, or chew the tablets.

This medication helps control blood sugar levels. However, it can very rarely cause a dangerous condition known as lactic acidosis, which requires caution. Lactic acidosis occurs when lactic acid accumulates excessively in the body and can be life-threatening in severe cases. Additionally, hypoglycemia can occur when taking this medication with insulin or other diabetes medications, so blood sugar status should be monitored closely. This medication should not be administered to patients with moderate or severe renal impairment. Patients with very poor cardiac function or acute kidney disease should not use this medication. If undergoing tests using radiologic iodine contrast agents, this medication should be stopped at least 48 hours prior to the test, and resumed only after confirming normal renal function post-examination. This medication is not used for type 1 diabetes patients or patients with diabetic ketoacidosis. Also, any patient who has had an allergic reaction to any components of this medication should avoid using it. In cases of severe infection, serious injury, before and after surgery, the use of this medication should be temporarily halted, and it should be resumed after renal function returns to normal. It is advisable for individuals with very poor nutritional status or impaired liver function, and those who consume alcohol excessively to avoid this medication. Pregnant women or women who may become pregnant should not take this medication, and breastfeeding mothers should consult their healthcare professional. During treatment with this medication, patients should be well aware of hypoglycemia symptoms and take immediate appropriate actions if symptoms appear. Additionally, this medication can cause side effects such as bowel obstruction, liver dysfunction, pneumonia, skin rashes, acute pancreatitis; if any of these symptoms occur, immediate consultation with a physician is necessary. Elderly patients may have reduced renal function, so regular kidney function tests should be conducted, and dose adjustments may be necessary. In case of overdose, immediate medical attention should be sought, and if necessary, blood dialysis may be performed to remove the drug. This medication has not established safety and efficacy in children, thus it is not used in pediatric patients. When storing the medication, it should be kept out of reach of children and not transferred to other containers. Finally, patients should avoid alcohol during treatment and consult their healthcare provider or pharmacist when combining with other medications.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, liver dysfunction, acute pancreatitis, lactic acidosis, severe allergic reactions, interstitial pneumonia, blistering dermatitis, lactic acidosis related symptoms (fatigue, myalgia, dyspnea, weakness, abdominal pain), hypoglycemia, severe edema, increased blood pressure, cerebral infarction, hepatic coma, sudden and severe headache, seizures, disorientation, visual disturbances, paralysis, pulmonary congestion, difficulty breathing, nodular skin lesions

Mild side effects

• Hypoglycemia
• constipation
• dizziness
• headache
• weakness
• hunger
• fatigue
• facial swelling
• diarrhea
• indigestion

This medication should be stored in a tightly closed container that does not allow air in, preferably at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the medication's efficacy over time.

Appearance

Yellow oval-shaped sustained-release film-coated tablets

Package unit

30 tablets/bottle