Dapagutine Tablet 5mg (Dapagliflozin Propanediol Hydrate)

Adult dose

The recommended dosage of this drug is 10 mg once daily for monotherapy and as an additional combination therapy with insulin and other blood glucose lowering agents. If this medication is used in combination with insulin or insulin secretagogues such as sulfonylureas, lower doses of insulin or insulin secretagogues may be considered to reduce the risk of hypoglycemia. For initial combination therapy with metformin, the initial recommended dose is 5 mg once daily or 10 mg once daily.

This drug should not be used in patients who have had an allergic reaction to the active ingredient or excipients, in patients with type 1 diabetes, or in patients undergoing dialysis. Care should be taken when used in patients with decreased fluid volume or poor kidney function, as hypotension or worsening kidney function may occur, so conditions should be carefully monitored before and after administration. The blood sugar control effect of this drug varies according to kidney function, so it is not recommended for patients with severely impaired kidney function. The most common side effect is genital infection, which may occur more frequently in women or patients with a history of infection, requiring caution. Hypoglycemic symptoms may appear, so especially when used with medications such as insulin or sulfonylureas, blood sugar changes should be closely monitored. Dehydration or symptoms of hypotension due to decreased body fluid may occur, so elderly patients or those taking diuretics should be particularly cautious. Severe metabolic disorder, known as diabetic ketoacidosis, may occur, so if related symptoms appear, immediate consultation with medical staff is required. Serious urinary infections such as urinary tract infection and pyelonephritis may occur, so prompt treatment is necessary if infection symptoms are present. The safety of this drug has not been sufficiently established for patients with severely impaired liver function, so caution is needed. Pregnant or breastfeeding women should avoid using this medication, and treatment should be discontinued immediately upon confirmation of pregnancy. For children, the safety and effectiveness of this drug have not been established, thus use is not recommended. In cases of overdose, there are no specific antidotes, so treatment should be symptomatic and follow medical staff instructions. Finally, this drug should be stored in its original container and kept out of reach of children.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucous membranes, shortness of breath or difficulty breathing, asthma attacks, respiratory complications with cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination.

Mild side effects

• Vulvar vaginitis
• balanitis and related genital infections
• urinary tract infection
• hypoglycemia
• thirst
• dizziness
• constipation
• dry mouth
• back pain
• dysuria

This medication should be stored in a container that is tightly sealed to avoid exposure to air or moisture and should be kept at room temperature between 1 degree and 30 degrees Celsius. Proper storage will maintain the drug's effectiveness and safety.

Appearance

Yellow round film-coated tablet

Package unit

28 tablets/box (7 tablets/Alu-Alu*4), 28 tablets/bottle