Rabeptap Tablets 20/800 mg (Rabeprazole Sodium, Sodium Bicarbonate)

Adult dose

For gastric ulcer and duodenal ulcer: Administer 20/800 mg orally once daily based on symptoms. Typically, treatment lasts up to 8 weeks for gastric ulcers and 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: Administer 20/800 mg orally once daily for 4 to 8 weeks. If the condition has not improved after 8 weeks of proton pump inhibitor (PPI) therapy, an additional 20/800 mg can be administered orally twice daily for another 8 weeks.

This medication contains Rabeprazole and Sodium Bicarbonate and should not be administered to certain patients. For example, patients with hypersensitivity to this drug, those taking specific medications such as Atazanavir and Rilpivirine, and pregnant or breastfeeding women should avoid its use. Caution should be exercised in patients with liver or kidney dysfunction, the elderly, and those with compromised cardiac or pulmonary function, and it is important to consult with the attending physician. This medication may cause various side effects, including skin rashes, hives, blood abnormalities, liver dysfunction, cardiovascular issues, gastrointestinal disturbances, and neurological abnormalities, so symptoms should be reported to healthcare personnel immediately. Regular blood tests and liver function tests are essential during long-term use, and if gastric ulcers or malignancies are suspected, specialized consultation is necessary. The Sodium Bicarbonate in this medication may cause alkalosis or edema, so careful observation of the condition is required. Additionally, this medication may interact with other drugs, so patients should inform healthcare personnel of any concurrent medications, and certain combinations should be avoided. Caution is advised when driving or operating machinery due to potential drowsiness, and pregnant or breastfeeding women should refrain from use. The elderly are at higher risk for side effects due to impaired liver function, so they should consult a doctor immediately if symptoms occur. The safety in children has not been established, so its use is not recommended. In cases of overdose, there is no specific antidote, and appropriate treatment should be administered based on symptoms. Tablets should not be chewed or crushed but swallowed whole. Store this medication out of reach of children and do not transfer it to other containers. Lastly, long-term use of this medication may increase the risk of gastric polyps, so it is advisable to take the minimum effective dose for the shortest duration.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, severe skin adverse reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellow discoloration of skin or eyes (jaundice), severe systemic lethargy, liver abnormalities (jaundice), sudden and severe headache, thunderclap headache, foot

Mild side effects

• Rash
• itching
• hemolytic anemia
• leukopenia
• leukocytosis
• eosinophilia
• neutrophilia
• lymphopenia
• anemia
• petechiae

This medication should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain a storage temperature between 1°C and 30°C. This will help safely retain the medication's effectiveness for a long time.

Appearance

White oval film-coated tablet

Package unit

28 tablets/box [7 tablets/PTP×4EA], 30 tablets/box [10 tablets/PTP×3EA]