Esriptin M Tablet 50/500 mg

Adult dose

This medication is generally taken twice a day with food, and the dosage is gradually increased to reduce gastrointestinal side effects caused by metformin. 1. For patients not currently receiving treatment with metformin: Take this medication 50/500 mg twice a day, one tablet at a time; the dosage can be increased to 50/1000 mg twice a day, one tablet at a time. 2. For patients already on metformin treatment: Sitagliptin

This medication contains sitagliptin and metformin, and is primarily used for the treatment of type 2 diabetes. The sitagliptin component may cause severe hypersensitivity reactions, skin disorders, or acute pancreatitis in some patients, so if these symptoms occur within 3 months after starting treatment, consult a physician immediately. The metformin component can cause a rare yet potentially fatal side effect called lactic acidosis, and should not be used in patients with impaired kidney function or liver dysfunction. Especially, it should not be administered to patients with moderate to severe renal impairment, acute heart failure, or acute myocardial infarction, as well as to patients with severe infections or dehydration, and administration should also be discontinued around the time of diagnostic tests using iodine contrast agents. It is not recommended for use in pregnant women or those who may become pregnant, nursing mothers, or children under 18 years of age. While taking this medication, be cautious of hypoglycemic symptoms when using other medications that may cause blood sugar lowering, particularly when used in combination with insulin or sulfonylureas, as the risk of hypoglycemia may increase. Moreover, patients engaging in vigorous exercise or those with irregular eating habits or nutritional imbalances should be particularly cautious while taking this medication. Regular monitoring of kidney function and blood tests should be performed while taking this medication, and since vitamin B12 levels may decline, supplementation may be necessary if needed. Alcohol consumption may increase the risk of lactic acidosis, so excessive drinking should be avoided while taking this medication. In cases of undergoing surgery or when oral intake is restricted, this medication should be temporarily discontinued 48 hours prior to surgery and can be resumed only after confirming normal kidney function post-recovery. Patients taking this medication should immediately inform healthcare providers and discontinue use if they notice any unusual symptoms such as skin rash, hives, difficulty breathing, sudden joint pain, or blistering skin conditions. In the event of overdose, general symptomatic treatment may be provided along with dialysis if necessary. Although clinical trials have confirmed that this medication does not increase the risk of cardiovascular diseases, caution is warranted based on the patient’s condition. Therefore, this medication should be taken precisely according to the physician's prescription and instructions, and immediate consultation with healthcare providers should be sought if any unusual symptoms arise.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, anaphylaxis, Stevens-Johnson syndrome, skin rash, skin peeling, pain in oral/ocular mucosa, acute pancreatitis, acute kidney failure, elevated liver enzymes, thrombocytopenia, severe neurological symptoms (severe headache, confusion, visual disturbances, paralysis), hypoglycemia (severe), lactic acidosis, respiratory distress, unstable angina, acute myocardial infarction, sepsis, acute heart failure,

Mild side effects

• Diarrhea
• upper respiratory infection
• headache
• nausea
• vomiting
• abdominal pain
• constipation
• nasopharyngitis
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container that is well-ventilated and kept at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness for a longer period.

Appearance

Bright pink oval film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP X 3]