Medication info
Dobe M Tablet 500 mg (Dopesilic Acid Calcium Hydrate)

Dobe M Tablet 500 mg (Dopesilic Acid Calcium Hydrate)

Prescription medicationTabletOral
Ingredient · strength
Dobesilate Calcium Hydrate›500mg / 1 tablet
Manufacturer / importer
Mothers Pharmaceutical Co., Ltd.
Appearance
White rectangular tablet
Packaging
10 tablets/bottle, 30 tablets/bottle, 90 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 202200251 · Approved 2022.01.14 · Insurance code 622804700

Summary

Main use
Treatment of capillary disorders (including diabetic retinopathy), venous diseases, and hemorrhoids
Who takes it
Adults
Adult dose
Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular damage and retinopathy: 500~1000mg daily 2. Venous disease: Administer 750mg daily for 1~3 weeks, then administer 500mg daily. Administer after meals with plenty of fluid. Adjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
Mothers Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of capillary disorders (including diabetic retinopathy), venous diseases, and hemorrhoids

  • Increased capillary rupture
  • permeability disorders
  • vascular damage
  • diabetic microangiopathy
  • diabetic retinopathy
  • venous insufficiency
  • post-thrombotic syndrome
  • peripheral venous edema
  • hemorrhoids
View approved original text

This medication is used for vascular damage caused by increased capillary rupture and permeability disorders, diabetic microangiopathy, diabetic retinopathy, venous insufficiency, post-thrombotic syndrome, peripheral venous edema, and conditions such as hemorrhoids.

How to take

Adult dose

Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular damage and retinopathy: 500~1000mg daily 2. Venous disease: Administer 750mg daily for 1~3 weeks, then administer 500mg daily. Administer after meals with plenty of fluid. Adjust the dose as appropriate according to age and symptoms.

Precautions

This medication contains Dopesilic Acid Calcium Hydrate as its active ingredient and should not be used in certain patients. For example, individuals who are allergic to this medication or its ingredients, women who are pregnant or breastfeeding, and those with genetic disorders that prevent lactose digestion should not take this medication. Patients with impaired kidney function should use caution. This medication is primarily excreted via urine, so individuals with reduced kidney function may need to adjust the dose. In particular, patients with severe renal failure requiring dialysis may need dosage reduction. Patients with impaired liver function should also take caution when using this medication. The safety and efficacy of this medication have not been sufficiently studied in individuals with liver dysfunction, and treatment should be reconsidered if liver enzyme levels are elevated. Additionally, this medication contains sulfite ingredients, which can cause serious allergic reactions in patients with sulfite allergies or asthma. Rarely, serious side effects such as agranulocytosis, which involves a reduction in blood cell counts, may occur while taking this medication. In such cases, symptoms of infection such as high fever, stomatitis, and sore throat may develop, and patients should notify their doctor immediately if symptoms occur and confirm their condition through blood tests. Furthermore, allergic reactions such as skin rashes, hives, and facial swelling, as well as severe allergic reactions such as anaphylaxis, may occur, and if these symptoms appear, the medication should be discontinued immediately. Common side effects may include headache, abdominal pain, nausea, diarrhea, vomiting, joint pain, muscle pain, and liver function abnormalities, and patients should consult a physician if these symptoms are severe. Interactions with other medications are not known; however, this medication may affect the measurement of creatinine levels during blood tests, so it should be reported before testing. Finally, before taking this medication for the first time, necessary tests such as blood tests should be performed to ensure safe use.

Side effects

  • Agranulocytosis
  • Neutropenia
  • Leukopenia
  • Skin rash
  • Allergic dermatitis
  • Itching
  • Urticaria
  • Facial swelling
  • Anaphylactic reaction
  • Headache
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  • Abdominal pain
  • Nausea
  • Diarrhea
  • Vomiting
  • Increased alanine aminotransferase
  • Arthralgia
  • Myalgia
  • Fever
  • Chills
  • Lethargy
  • Fatigue

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container that blocks light, at a temperature between 1 degree and 30 degrees Celsius. Storing it this way will help maintain the medication's efficacy and prevent degradation.

Appearance and packaging

Appearance

White rectangular tablet

Package unit

10 tablets/bottle, 30 tablets/bottle, 90 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.