Sitaren Duo Tablets 50/1000 mg (Sitagliptin, Metformin Hydrochloride)

Adult dose

This medication is generally taken twice daily with food and the dosage is increased gradually to minimize gastrointestinal side effects caused by metformin. 1. Patients not currently treated with metformin: - The initial dosage is 50/500 mg of this medication taken twice daily, with a potential increase to 50/1000 mg taken twice daily at one tablet per dose. 2. Patients being treated with metformin:

This medication is used for diabetes treatment and contains two active ingredients, sitagliptin and metformin. During treatment with this medication, allergic reactions may occur; therefore, if symptoms such as skin rash or difficulty breathing arise, discontinue use immediately and consult a physician. There may be a risk of acute pancreatitis, so if symptoms such as abdominal pain, nausea, or vomiting occur, monitor closely and inform your doctor. This medication should not be used in patients with impaired kidney function, acute heart issues, or those who are pregnant or breastfeeding. Particularly, patients with reduced kidney function should have thorough discussions with their physician before taking this medication and should undergo regular kidney function tests. Moreover, during acute infections, dehydration, or before and after significant trauma or surgery, it may be necessary to temporarily discontinue this medication. When taking this medication, if meal amounts are irregular or if engaging in strenuous exercise, there is a risk of side effects such as hypoglycemia or lactic acidosis; caution is advised. Side effects such as diarrhea, nausea, headache, and upper respiratory infections may occur, and immediate treatment is required in cases of severe hypoglycemia. Additionally, this medication may have interactions if taken with other hypoglycemic agents or certain medications, so inform your doctor of all medications being taken. Alcohol consumption may increase the risk of lactic acidosis; therefore, it is advisable to avoid drinking during treatment. If undergoing surgery or contrast studies using iodine, the use of this medication should be suspended for a certain period, and it should only be resumed after confirming that kidney function is normal. Elderly individuals may have a higher risk of diminished kidney function, so kidney function should be monitored more carefully during treatment with this medication. Pregnant women or those who might become pregnant and breastfeeding mothers should not use this medication. If an overdose occurs, seek medical attention immediately, as this medication can be partially removed by dialysis. Finally, if any abnormal symptoms develop during treatment with this medication, consult a doctor immediately and continue treatment with regular monitoring of blood sugar and kidney function.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, chest tightness, difficulty breathing, Stevens-Johnson syndrome, severe rash accompanied by fever, blisters, skin peeling, pain in oral/ocular mucosa, acute pancreatitis, acute renal failure, liver dysfunction (jaundice), severe lactic acidosis, sudden and very severe headache, seizures, altered consciousness, visual disturbances, paralysis, severe swelling with elevated blood pressure, significantly reduced urine output, difficulty breathing,

Mild side effects

Diarrhea, nausea, vomiting, abdominal pain, upper respiratory infection, nasopharyngitis, headache, hypoglycemia, constipation, weakness, myalgia, limb pain, back pain, pruritus, thrombocytopenia, decreased appetite, itching, dizziness, weight loss, dermatitis, metabolic abnormalities, psychiatric symptoms, bullous pemphigoid, severe and disability-associated arthralgia

This medication should be stored in a tightly closed container to prevent air from entering, at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the medication's efficacy and prevent deterioration.

Appearance

Pink oval film-coated tablets

Package unit

30 tablets/box [(10 tablets/PTP x 3)]