Samsitaplus Tablet 50/850 mg

Adult dose

This medication is generally taken orally twice daily with food, and the dosage is gradually increased to minimize gastrointestinal side effects from metformin. 1. Patients currently not treated with metformin: Take this medication 50/500 mg twice daily, 1 tablet at a time, and may increase to 50/1000 mg twice daily, 1 tablet at a time. 2. Patients currently receiving treatment with metformin

This medication is used in the treatment of diabetes and contains sitagliptin and metformin. When taking this medication, severe allergic reactions may occur, so if symptoms such as skin rash or difficulty in breathing appear, stop taking it immediately and consult a doctor. Additionally, symptoms of acute pancreatitis may occur, so if abdominal pain, nausea, or vomiting occurs, inform the healthcare provider immediately. This medication should not be administered to patients with severely impaired kidney function, severe infections or dehydration, acute heart failure, or women who are pregnant or breastfeeding. Particularly, this medication should be discontinued before tests using iodine contrast agents, and should not be resumed until kidney function is confirmed to be normal after the test. This medication may cause hypoglycemia, so caution is advised when meal intake is irregular or physical activity drastically increases. The risk of hypoglycemia may increase when taken with insulin or sulfonylureas. During treatment, regular monitoring of kidney function and blood tests should be conducted for any abnormalities, and vitamin B12 levels may decrease, so supplementation may be necessary if required. Alcohol may increase the risk of side effects related to this medication, so it is advisable to avoid drinking alcohol during treatment. In case of surgery or severe trauma, this medication should be temporarily discontinued, and it can be resumed after confirming that the patient is capable of oral intake and their kidney function is normal. This medication poses a higher risk of kidney function decline in elderly patients, thus dose adjustments and regular monitoring are necessary. In the event of an overdose, notify healthcare personnel immediately, and treatment such as hemodialysis may be necessary. Any abnormal symptoms or discomfort during treatment should be discussed with a doctor or pharmacist.

Serious side effects

Hives, severe angioedema, anaphylaxis, Stevens-Johnson syndrome, exfoliative skin disease, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucous membranes, difficulty breathing, asthma attacks, jaundice, liver dysfunction, acute pancreatitis, acute kidney failure, severe edema, severe neurological symptoms (severe headache, confusion, seizures, visual disturbances, paralysis), severe arthralgia, bullous pemphigoid, thrombocytopenia, acute

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory infection
• nasopharyngitis
• headache
• hypoglycemia
• constipation
• weakness

Store this medication in a tightly closed container, protecting it from air, and keep it at room temperature between 1 to 30 degrees Celsius. This helps maintain the effectiveness of the medication for a longer duration.

Appearance

Pink oval film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP×3)]