Itex Desmopressin Tablets 0.1 mg (Desmopressin Acetate)

Adult dose

Treatment of nocturia associated with nocturnal polyuria (adults only): Administer desmopressin acetate 0.1mg orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg; if the effect remains insufficient, the dose may be increased at one-week intervals up to 0.4mg. Discontinue treatment if there is no clinical effect within 4 weeks after dose titration. Initiation of treatment with this medicine is not recommended in patients 65 years of age and older. In older patients who require treatment, monitor serum sodium levels closely. (See 5. General Precautions in Precautions for Use.)

Child dose

Primary nocturnal enuresis (5 years of age and older): Administer 0.2mg of desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased up to 0.4mg. Whether to continue treatment should be determined after 3 months of administration, following discontinuation of treatment for at least 1 week.

This drug affects water regulation in the body, so elderly patients or patients with certain diseases may experience hyponatremia and water intoxication; therefore, fluid intake should be limited to the point of thirst only. Patients with a history of allergic reactions to this drug's ingredients, severely impaired kidney function, or abnormally high urine output due to habitual or psychological causes should not use this medication. Patients with hypertension, heart disease, chronic kidney disease, pregnant women, children, and elderly patients should use this drug with great caution and should be administered under strict medical supervision if necessary. During the use of this drug, side effects such as hyponatremia, headache, nausea, weight gain, and seizures may occur, so if any abnormal symptoms arise, immediate consultation with a healthcare professional is advised. Fluid intake should be restricted from one hour before taking the drug to eight hours after taking it, and during kidney function tests, it should be limited to less than 0.5 liters for 12 hours. Failure to limit fluid intake may lead to fluid retention or the risk of hyponatremia. This drug may interact with other medications, so particularly when used with antidepressants, diuretics, corticosteroids, and anticonvulsants, blood tests and symptom monitoring are necessary. Women who are pregnant or may become pregnant must consult their physician before using this drug, and nursing mothers are advised to discontinue breastfeeding while using this medication. In case of overdose, symptoms such as headache, nausea, seizures, and loss of consciousness may appear; thus, dosage should be adjusted according to symptoms and fluid intake should be restricted. In severe cases, appropriate treatment should be received at a hospital.

• coma
• convulsions
• weight gain
• severe water intoxication
• hyponatremia
• allergic reactions
• emotional disturbances
• headache
• abdominal pain
• nausea

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

White oval tablets

Package unit

30 tablets/bottle