BildaMet Tablet 50/500 mg

Adult dose

The dosage of this medication should be individualized based on efficacy and tolerance, not exceeding vildagliptin 100 mg and metformin 2000 mg. A daily dose of vildagliptin greater than 100 mg is not recommended. This medication is generally administered with food or shortly after meals to reduce gastrointestinal side effects caused by metformin. 1. For patients with no prior experience with diabetes medications and insufficient blood sugar control with monotherapy: The initial dose of this medication is 50/500 mg once daily, with gradual increase possible to 50/1000 mg twice daily, one tablet at a time. 2. For patients switching from combination therapy of vildagliptin and metformin: Patients transitioning to this medication from combination therapy may start at the existing doses of vildagliptin and metformin. No studies have been conducted to review the safety and efficacy of switching from other oral hypoglycemic agents to this medication. Any changes in type 2 diabetes treatment may affect blood sugar control, thus careful monitoring is required. If a dose is missed, take it at the next meal as long as it is not the time for the next dose, and do not double the dose to make up for a missed dose. In patients with liver dysfunction: This medication is not recommended for patients with clinical or laboratory evidence of liver dysfunction, including those with ALT or AST levels exceeding 2.5 times the upper limit of normal prior to administration.

This medication has the potential to cause severe lactic acidosis or hypoglycemia, and caution is required. It should not be used in patients with moderate to severe renal dysfunction or those with heart failure or liver dysfunction. Additionally, it should be temporarily discontinued in cases of acute infections, severe trauma, or unstable physical conditions such as pre- and post-surgery. It should also not be administered to pregnant or nursing women. It is important to maintain regular meals and appropriate exercise during the use of this medication, and interactions with other medications should be considered. In particular, alcohol consumption may increase the risk of lactic acidosis and should be avoided. This medication should be regularly monitored for liver and kidney function, and any unusual symptoms should be reported to healthcare professionals immediately. If symptoms of hypoglycemia occur, it is necessary to intake appropriate sugars immediately. Activities that require alertness, such as driving or operating machinery, should be avoided in the presence of dizziness or symptoms of hypoglycemia. Keep out of reach of children, and do not transfer to another container arbitrarily.

Serious side effects

• Hives
• angioedema
• blistering and exfoliative skin lesions
• hepatitis
• jaundice
• severe lactic acidosis
• severe hypoglycemia
• acute pancreatitis
• bullous pemphigoid
• severe and disabling joint pain

Mild side effects

• Tremor
• headache
• dizziness
• fatigue
• nausea
• hypoglycemia
• gastroesophageal reflux
• diarrhea
• bloating
• chills

This medication should be stored in a tightly sealed container to prevent air and moisture from entering, and should be kept in a cool place below 30 degrees Celsius to maintain efficacy.

Appearance

Bright yellow oval film-coated tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 60 tablets/bottle